An updated review of folate-functionalized nanocarriers: A promising ligand in cancer

P Ebrahimnejad, AS Taleghani, K Asare-Addo… - Drug discovery today, 2022 - Elsevier
The uncontrolled release of drugs in conventional drug delivery systems has led to the
introduction of new nanotechnology-based drug delivery systems and the use of targeted …

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy

B Bahrami, M Mohammadnia-Afrouzi, P Bakhshaei… - Tumor Biology, 2015 - Springer
The selective and efficient drug delivery to tumor cells can remarkably improve different
cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a …

Folate-mediated chemotherapy and diagnostics: an updated review and outlook

L Xu, Q Bai, X Zhang, H Yang - Journal of controlled release, 2017 - Elsevier
Folate receptor (FR) is highly expressed in many types of human cancers, and it has been
actively studied for developing targeted chemotherapy and diagnostic agents. Tremendous …

Utilizing the folate receptor for active targeting of cancer nanotherapeutics

GL Zwicke, G Ali Mansoori, CJ Jeffery - Nano reviews, 2012 - Taylor & Francis
The development of specialized nanoparticles for use in the detection and treatment of
cancer is increasing. Methods are being proposed and tested that could target treatments …

Folate-conjugated nanovehicles: Strategies for cancer therapy

B Farran, RC Montenegro, P Kasa, E Pavitra… - Materials Science and …, 2020 - Elsevier
Cancer theranostics represents a strategy that aims at combining diagnosis with therapy
through the simultaneous imaging and targeted delivery of therapeutics to cancer cells …

[HTML][HTML] Active targeted nanoformulations via folate receptors: State of the art and future perspectives

C Martín-Sabroso, AI Torres-Suárez… - Pharmaceutics, 2021 - mdpi.com
In normal tissues, the expression of folate receptors is low and limited to cells that are
important for embryonic development or for folate reabsorption. However, in several …

In search of the Holy Grail: folate-targeted nanoparticles for cancer therapy

A Garcia-Bennett, M Nees, B Fadeel - Biochemical pharmacology, 2011 - Elsevier
Targeted drug therapy or “smart” drug delivery, potentially combined with simultaneous
imaging modalities to monitor the delivery of drugs to specific tissues, is arguably the “holy …

Potential applications of Folate-conjugated Chitosan Nanoparticles for Targeted delivery of Anticancer drugs

PNK Sarella, PK Thammana - 2023 - indianjournals.com
Folate-conjugated chitosan nanoparticles represent a promising nanoplatform for targeted
delivery of anticancer drugs. The nanoparticle carrier can protect the therapeutic agents from …

Folic acid functionalized nanoparticles as pharmaceutical carriers in drug delivery systems

A Narmani, M Rezvani, B Farhood… - Drug development …, 2019 - Wiley Online Library
Conventional chemotherapeutic approaches in cancer therapy such as surgery,
chemotherapy, and radiotherapy have several disadvantages due to their nontargeted …

Recent advances in folic acid engineered nanocarriers for treatment of breast cancer

P Tagde, GT Kulkarni, DK Mishra… - Journal of Drug Delivery …, 2020 - Elsevier
Breast cancer is one of the most prevalent types of cancer among female patients, which is
caused by mutations in the oestrogen/progesterone receptors. Conventional treatment …