The cause and effect of Cryptococcus interactions with the host

ER Ballou, SA Johnston - Current opinion in microbiology, 2017 - Elsevier
Upon Cryptococcus neoformans infection of the host lung, the fungus enters a nutrient poor
environment and must adapt to a variety of host-specific stress conditions (temperature …

Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence

J Kronstad, S Saikia, ED Nielson, M Kretschmer… - Eukaryotic …, 2012 - Am Soc Microbiol
The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of
desiccated yeast cells or spores from the environment. In the absence of effective immune …

[HTML][HTML] Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes

EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …

[HTML][HTML] Innate Immune Responses to Cryptococcus

LJ Heung - Journal of fungi, 2017 - mdpi.com
Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …

[HTML][HTML] Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome

CM Leopold Wager, CR Hole, KL Wozniak… - Frontiers in …, 2016 - frontiersin.org
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

[HTML][HTML] Environmental Factors That Contribute to the Maintenance of Cryptococcus neoformans Pathogenesis

M Maliehe, MA Ntoi, S Lahiri, OS Folorunso… - Microorganisms, 2020 - mdpi.com
The ability of microorganisms to colonise and display an intracellular lifestyle within a host
body increases their fitness to survive and avoid extinction. This host–pathogen association …

The tools for virulence of Cryptococcus neoformans

C Coelho, AL Bocca, A Casadevall - Advances in applied microbiology, 2014 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …

Macrophage–Cryptococcus Interactions: An Update

MK Mansour, JL Reedy, JM Tam, JM Vyas - Current fungal infection …, 2014 - Springer
Cryptococcus species are fungal pathogens that are a leading cause of mortality. Initial
inoculation is through the pulmonary route and, if disseminated, results in severe invasive …

Virulence mechanisms and Cryptococcus neoformans pathogenesis

JA Alspaugh - Fungal Genetics and Biology, 2015 - Elsevier
The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …