Phenotyping the pathophysiology of obstructive sleep apnea using polygraphy/polysomnography: a review of the literature
M Bosi, A De Vito, B Kotecha, L Viglietta… - Sleep and …, 2018 - Springer
Continuous positive airway pressure (CPAP) is the first-line treatment for the majority of
patients affected by obstructive sleep apnea syndrome (OSA). However, long-term …
patients affected by obstructive sleep apnea syndrome (OSA). However, long-term …
[HTML][HTML] Sleep apnea endotypes: from the physiological laboratory to scalable polysomnographic measures
Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent upper
airway obstruction during sleep. Despite the availability of continuous positive airway …
airway obstruction during sleep. Despite the availability of continuous positive airway …
A novel model to estimate key obstructive sleep apnea endotypes from standard polysomnography and clinical data and their contribution to obstructive sleep apnea …
Rationale: There are at least four key pathophysiological endotypes that contribute to
obstructive sleep apnea (OSA) pathophysiology. These include 1) upper-airway …
obstructive sleep apnea (OSA) pathophysiology. These include 1) upper-airway …
Phenotyping pharyngeal pathophysiology using polysomnography in patients with obstructive sleep apnea
Rationale: Therapies for obstructive sleep apnea (OSA) could be administered on the basis
of a patient's own phenotypic causes (“traits”) if a clinically applicable approach were …
of a patient's own phenotypic causes (“traits”) if a clinically applicable approach were …
Opportunities for utilizing polysomnography signals to characterize obstructive sleep apnea subtypes and severity
DR Mazzotti, DC Lim, K Sutherland… - Physiological …, 2018 - iopscience.iop.org
Background: Obstructive sleep apnea (OSA) is a heterogeneous sleep disorder with many
pathophysiological pathways to disease. Currently, the diagnosis and classification of OSA …
pathophysiological pathways to disease. Currently, the diagnosis and classification of OSA …
OSA endotypes: what are they and what are their potential clinical implications?
Abstract Purpose of the Review To review critically the different mechanisms, or endotypes,
causing obstructive sleep apnea (OSA) in individual patients, and their potential implications …
causing obstructive sleep apnea (OSA) in individual patients, and their potential implications …
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets
Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among
patients but have not been well characterized. Objectives: To define carefully the proportion …
patients but have not been well characterized. Objectives: To define carefully the proportion …
Pro: can physiological risk factors for obstructive sleep apnea be determined by analysis of data obtained from routine polysomnography?
SA Sands, BA Edwards - Sleep, 2023 - academic.oup.com
The following argument was prepared in response to the question without the knowledge of
the contents of the opposing argument. Obstructive sleep apnea (OSA) is a highly prevalent …
the contents of the opposing argument. Obstructive sleep apnea (OSA) is a highly prevalent …
Obstructive sleep apnea: current perspectives
AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …
safety, and economic consequences. On an individual level, the causes and consequences …
A simplified method for determining phenotypic traits in patients with obstructive sleep apnea
We previously published a method for measuring several physiological traits causing
obstructive sleep apnea (OSA). The method, however, had a relatively low success rate …
obstructive sleep apnea (OSA). The method, however, had a relatively low success rate …