When administered into the brain, NPY acts at Y1 and Y5 receptors to increase food intake.
The response occurs with a short latency and is quite robust, such that exogenous NPY is …

The aim of this review is to critically assess the evidence that neuropeptide Y (NPY) plays
both an important role in the control of food intake and in the peripheral metabolic processes …

Neuropeptide Y (NPY) is one the most potent orexigenic peptides found in the brain. It
stimulates food intake with a preferential effect on carbohydrate intake. It decreases latency …

During the past decade, a detailed understanding has emerged of the aminergic and
peptidergic neural pathways present within the brain that regulate appetite. Central among …

Feeding behavior is tightly regulated by peptidergic transmission within the hypothalamus.
Neuropeptide Y (NPY) is one of the most potent known stimulators of food intake and has …

To differentiate NPY receptor subtypes, Y 1 and Y 2, in terms of their impact on feeding
behavior, the intact molecule NPY (1–36) and the 3 fragments, NPY (2–36), the Y 1 agonist …

Clark and colleagues first described the robust orexigenic effects of neuropeptide Y (NPY) in
1984. Our group as well as Stanley et al. confirmed these effects in the same year. During …

Publisher Summary This chapter critically reviews evidence of physiologically relevant
appetite stimulation by neuropeptide Y (NPY) and to forecast how this knowledge might be …

Neuropeptide Y (NPY) is a 36 amino acid amidated peptide which has now emerged as an
important regulator of feeding behaviour. Upon intracerebroventricular (icv.) administration …

Neuropeptide Y (NPY), administered intracerebroventricularly, is a potent orexigenic agent.
To determine if NPY-induced eating represented an increase in motivation to eat (eg …