Obesity is emerging as a global public health epidemic. The co-morbidities associated with
obesity significantly contribute to reduced quality of life, mortality, and global healthcare …

The pathogenesis of asthma includes a complex interplay among airway inflammation,
hyperresponsiveness, and remodeling. Current evidence suggests that airway structural …

Asthma is a chronic disease of the airways affecting around 10% of the population. The
majority of cases are well controlled with current therapies, however in approximately 20 …

Transforming growth factor-β (TGF-β) is an important fibrogenic and immunomodulatory
factor that may play a role in the structural changes observed in the asthmatic airways. In …

Airway diseases such as chronic rhinosinusitis, asthma, and chronic obstructive pulmonary
disorder are characterized by inflammation and remodeling. Among inflammatory and …

Transforming growth factor‐beta 1 (TGF‐β1) has been reported being involved in the
remodeling and immunosuppression processes of inflammatory airway diseases; …

Asthma, chronic obstructive pulmonary disorder (COPD), and cystic fibrosis (CF), chronic
diseases of the airways, are characterized by symptoms such as inflammation of the lung …

TGF-β is one of the main mediators involved in tissue remodeling in the asthmatic lung. This
profibrotic cytokine is produced by a number of cells, including macrophages, epithelial …

Asthma is a waxing and waning disease that leads to structural changes in the airways, such
as subepithelial fibrosis, increased mass of airway smooth muscle and epithelial metaplasia …

Asthma is a chronic inflammatory airway disease involving complex interplay between
resident and infiltrative cells, which in turn are regulated by a wide range of host mediators …