Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota
AE Lindell, M Zimmermann-Kogadeeva… - Nature Reviews …, 2022 - nature.com
The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …
Antibiotic effects on gut microbiota, metabolism, and beyond
Current advances on gut microbiota have broadened our view on host-microbiota
interactions. As a microbiota-targeted approach, the use of antibiotics has been widely …
interactions. As a microbiota-targeted approach, the use of antibiotics has been widely …
Xenobiotics: interaction with the intestinal microflora
K Lu, R Mahbub, JG Fox - ILAR journal, 2015 - academic.oup.com
The human body is host to 100 trillion gut microbes, approximately 10-times more than all
human cells. It is estimated that the approximately 500–1000 species residing in the human …
human cells. It is estimated that the approximately 500–1000 species residing in the human …
Systematically investigating the impact of medication on the gut microbiome
Highlights•Association studies report drug-mediated changes in microbiome signatures.•
Interactions with the microbiome can be part of a drug's mode of action or side effects.• …
Interactions with the microbiome can be part of a drug's mode of action or side effects.• …
Gut microorganisms, mammalian metabolism and personalized health care
The mammalian gut microbiota interact extensively with the host through metabolic
exchange and co-metabolism of substrates. Such metabolome–metabolome interactions are …
exchange and co-metabolism of substrates. Such metabolome–metabolome interactions are …
[HTML][HTML] Host-microbial interactions in the metabolism of therapeutic and diet-derived xenobiotics
RN Carmody, PJ Turnbaugh - The Journal of clinical …, 2014 - Am Soc Clin Investig
Our associated microbial communities play a critical role in human health and predisposition
to disease, but the degree to which they also shape therapeutic interventions is not well …
to disease, but the degree to which they also shape therapeutic interventions is not well …
Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens
SL Vogt, J Peña-Díaz, BB Finlay - Anaerobe, 2015 - Elsevier
Gastrointestinal pathogens must overcome many obstacles in order to successfully colonize
a host, not the least of which is the presence of the gut microbiota, the trillions of commensal …
a host, not the least of which is the presence of the gut microbiota, the trillions of commensal …
Integrating the gut microbiome and pharmacology
AA Verdegaal, AL Goodman - Science Translational Medicine, 2024 - science.org
The gut microbiome harbors trillions of organisms that contribute to human health and
disease. These bacteria can also affect the properties of medical drugs used to treat these …
disease. These bacteria can also affect the properties of medical drugs used to treat these …
Interaction between drugs and the gut microbiome
The human gut microbiome is a complex ecosystem that can mediate the interaction of the
human host with their environment. The interaction between gut microbes and commonly …
human host with their environment. The interaction between gut microbes and commonly …
[HTML][HTML] Gut microbiota as an “invisible organ” that modulates the function of drugs
X Li, L Liu, Z Cao, W Li, H Li, C Lu, X Yang… - Biomedicine & …, 2020 - Elsevier
Gut microbiota plays an important role in the gut and have become a hotspot of recent
research interests. Commensal microbiota in gut exert a variety of effects on the host, from …
research interests. Commensal microbiota in gut exert a variety of effects on the host, from …