Gene delivery strategies for therapeutic proteins production in plants: Emerging opportunities and challenges
There are sharply rising demands for pharmaceutical proteins, however shortcomings
associated with traditional protein production methods are obvious. Genetic engineering of …
associated with traditional protein production methods are obvious. Genetic engineering of …
Nanoparticle-mediated delivery towards advancing plant genetic engineering
Genetic engineering of plants has enhanced crop productivity in the face of climate change
and a growing global population by conferring desirable genetic traits to agricultural crops …
and a growing global population by conferring desirable genetic traits to agricultural crops …
Therapeutic recombinant protein production in plants: Challenges and opportunities
MJB Burnett, AC Burnett - Plants, People, Planet, 2020 - Wiley Online Library
Societal Impact Statement Therapeutic protein production in plants is an area of great
potential for increasing and improving the production of proteins for the treatment or …
potential for increasing and improving the production of proteins for the treatment or …
Gene delivery into plant cells for recombinant protein production
Recombinant proteins are primarily produced from cultures of mammalian, insect, and
bacteria cells. In recent years, the development of deconstructed virus‐based vectors has …
bacteria cells. In recent years, the development of deconstructed virus‐based vectors has …
A nano-biomimetic transformation system enables in planta expression of a reporter gene in mature plants and seeds
Plant genetic engineering will be essential to decipher the genomic basis of complex traits,
optimize crop genomics, and enable plant-based production of recombinant proteins …
optimize crop genomics, and enable plant-based production of recombinant proteins …
Transgenic plants for therapeutic proteins: linking upstream and downstream strategies
CL Cramer, JG Boothe, KK Oishi - Plant biotechnology: new products and …, 2000 - Springer
With the new knowledge generated through the Human Genome Project and related
biomedical research comes a potential revolution in drug development strategies. One of the …
biomedical research comes a potential revolution in drug development strategies. One of the …
Organelle-targeted gene delivery in plants by nanomaterials
Genetic engineering of plants has revolutionized agriculture and has had a significant
impact on our everyday life. It has allowed for the production of crops with longer shelf lives …
impact on our everyday life. It has allowed for the production of crops with longer shelf lives …
[HTML][HTML] Agroinfiltration as an effective and scalable strategy of gene delivery for production of pharmaceutical proteins
Current human biologics are most commonly produced by mammalian cell culture-based
fermentation technologies. However, its limited scalability and high cost prevent this platform …
fermentation technologies. However, its limited scalability and high cost prevent this platform …
Production of heterologous proteins in plants: strategies for optimal expression
PN Desai, N Shrivastava, H Padh - Biotechnology advances, 2010 - Elsevier
Plants are a promising expression system for the production of heterologous proteins,
especially therapeutic proteins. Currently the majority of therapeutic proteins are produced …
especially therapeutic proteins. Currently the majority of therapeutic proteins are produced …
Nanomaterial based gene delivery: a promising method for plant genome engineering
SK Jat, J Bhattacharya, MK Sharma - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Nanomaterials have attracted considerable attention from researchers in recent years due to
their unique architecture and small dimensions. Significant progress has been made in the …
their unique architecture and small dimensions. Significant progress has been made in the …