Immunotherapy for hepatocellular carcinoma: the next evolution in expanding access to liver transplantation

M Li, S Bhoori, N Mehta, V Mazzaferro - Journal of Hepatology, 2024 - Elsevier
Immunotherapy has revolutionized treatment of advanced hepatocellular carcinoma (HCC).
In addition, several phase III trials of immunotherapy in early-to intermediate-stage HCC in …

Immunotherapy for hepatocellular carcinoma in the setting of liver transplantation: A review

Z Lominadze, K Hill, MR Shaik, JP Canakis… - International Journal of …, 2023 - mdpi.com
The emerging field of immuno-oncology has brought exciting developments in the treatment
of hepatocellular carcinoma (HCC). It has also raised urgent questions about the role of …

[HTML][HTML] When immunotherapy meets liver transplantation for hepatocellular carcinoma: a bumpy but promising road

Y Gu, S Xu, Z Wang, J Yang, S Zheng… - Chinese Journal of …, 2023 - ncbi.nlm.nih.gov
Liver transplantation (LT) is a highly curative therapy for patients with hepatocellular
carcinoma (HCC). However, due to the shortage of donor livers and rapid progression of …

[HTML][HTML] Immunotherapy in liver transplantation for hepatocellular carcinoma: Pros and cons

Y Luo, F Teng, H Fu, GS Ding - World journal of gastrointestinal …, 2022 - ncbi.nlm.nih.gov
Liver transplantation (LT) has emerged as a curative strategy for hepatocellular carcinoma
(HCC), but contributes to a higher predisposition to HCC recurrence in the …

Preoperative immunotherapy in hepatocellular carcinoma: Current state of the art

A Laschtowitz, C Roderburg, F Tacke… - Journal of …, 2023 - Taylor & Francis
Hepatocellular carcinoma (HCC) is a malignancy that requires multidisciplinary evaluation
to develop individualized and tailored treatment concepts. While liver resection and …

The use of immuno-oncologic therapy in hepatocellular carcinoma in the context of liver transplantation. An interdisciplinary benefit/risk assessment

A Vogel, M Sterneck, F Vondran… - Zeitschrift fur …, 2021 - europepmc.org
Background Multiple systemic therapy options have been recently approved for the
treatment of hepatocellular carcinoma (HCC). In particular, immuno-oncology combination …

Immunotherapy for transplantation of hepatocellular carcinoma: the next frontier in adjunctive therapy

P Tabrizian, M Zeitlhoefler, AT Hassan… - Current Opinion in …, 2024 - journals.lww.com
Initial concerns about graft rejection, with ICIs as a bridging therapy to liver transplantation,
were successfully addressed using adequate immunosuppressants strategies and …

Immunotherapy as a Complement to Surgical Management of Hepatocellular Carcinoma

SJ Kim, KC Cummins, A Tsung - Cancers, 2024 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the most common primary liver tumor
in adults worldwide. Management of HCC has evolved substantially with the advent of …

Immunotherapy of hepatocellular carcinoma: recent progress and new strategy

J Li, S Xuan, P Dong, Z Xiang, C Gao, M Li… - Frontiers in …, 2023 - frontiersin.org
Due to its widespread occurrence and high mortality rate, hepatocellular carcinoma (HCC) is
an abhorrent kind of cancer. Immunotherapy is a hot spot in the field of cancer treatment …

Trial watch: immunotherapeutic strategies on the horizon for hepatocellular carcinoma

B Koh, DJH Tan, WH Lim, JSL Wong, CH Ng… - …, 2023 - Taylor & Francis
The use of immune checkpoint inhibitors (ICIs) targeting PD-L1/PD-1 and CTLA-4 has
transformed the oncology practice of hepatocellular carcinoma. However, only 25–30% of …