Developmental regulation of axon branching in the vertebrate nervous system

DA Gibson, L Ma - Development, 2011 - journals.biologists.com
During nervous system development, axons generate branches to connect with multiple
synaptic targets. As with axon growth and guidance, axon branching is tightly controlled in …

Branch management: mechanisms of axon branching in the developing vertebrate CNS

K Kalil, EW Dent - Nature Reviews Neuroscience, 2014 - nature.com
The remarkable ability of a single axon to extend multiple branches and form terminal arbors
enables vertebrate neurons to integrate information from divergent regions of the nervous …

[HTML][HTML] Signaling mechanisms in cortical axon growth, guidance, and branching

K Kalil, L Li, BI Hutchins - Frontiers in neuroanatomy, 2011 - frontiersin.org
Precise wiring of cortical circuits during development depends upon axon extension,
guidance, and branching to appropriate targets. Motile growth cones at axon tips navigate …

Initiating and growing an axon

F Polleux, W Snider - Cold Spring Harbor perspectives …, 2010 - cshperspectives.cshlp.org
The ability of neurons to form a single axon and multiple dendrites underlies the directional
flow of information transfer in the central nervous system. Dendrites and axons are …

Mechanistic advances in axon pathfinding

LE McCormick, SL Gupton - Current opinion in cell biology, 2020 - Elsevier
The development of a functional nervous system entails establishing connectivity between
appropriate synaptic partners. During axonal pathfinding, the developing axon navigates …

Signaling mechanisms of axon guidance and early synaptogenesis

MA Robichaux, CW Cowan - The neurobiology of childhood, 2014 - Springer
The development of the vertebrate nervous system, including the brain and spinal cord,
progresses in a step-wise fashion that involves the function of thousands of genes. The birth …

Differential outgrowth of axons and their branches is regulated by localized calcium transients

BI Hutchins, K Kalil - Journal of Neuroscience, 2008 - Soc Neuroscience
During development axon outgrowth and branching are independently regulated such that
axons can stall or retract while their interstitial branches extend toward targets. Previous …

Wiring of the brain by a range of guidance cues

N Yamamoto, A Tamada, F Murakami - Progress in neurobiology, 2002 - Elsevier
During development of the central nervous system, growth cones navigate along specific
pathways, recognize their targets and then form synaptic connections by elaborating …

Mechanisms of axon guidance in the developing nervous system

C Plachez, LJ Richards - Current topics in developmental biology, 2005 - Elsevier
The human brain assembles an incredible network of over a billion neurons. Understanding
how these connections form during development in order for the brain to function properly is …

The role of neural activity in cortical axon branching

N Uesaka, ES Ruthazer, N Yamamoto - The Neuroscientist, 2006 - journals.sagepub.com
Axonal branching is an important process for establishing the final pattern of connections
between a neuron and its target cells. Cortical connections between upper-layer cells in the …