Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis

H Zhang, SM Moochhala, M Bhatia - The Journal of Immunology, 2008 - journals.aai.org
Hydrogen sulfide (H 2 S) up-regulates inflammatory response in several inflammatory
diseases. However, to date, little is known about the molecular mechanism by which H 2 S …

Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines …

H Zhang, L Zhi, S Moochhala… - American Journal of …, 2007 - journals.physiology.org
Recent studies have implied that hydrogen sulfide (H2S) plays a crucial role in several
inflammatory conditions. However, so far little is known about the mechanism by which H2S …

Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis

H Zhang, L Zhi, SM Moochhala… - Journal of Leucocyte …, 2007 - academic.oup.com
Hydrogen sulfide (H2S) is recognized increasingly as a proinflammatory mediator in various
inflammatory conditions. Here, we have investigated the role of H2S in regulating …

Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse

H Zhang, L Zhi, PK Moore… - American Journal of …, 2006 - journals.physiology.org
Endogenous hydrogen sulfide (H2S) is naturally synthesized in various types of mammalian
cells from l-cysteine in a reaction catalyzed by two enzymes, cystathionine-γ-lyase (CSE) …

[HTML][HTML] Hydrogen sulfide and neurogenic inflammation in polymicrobial sepsis: involvement of substance P and ERK-NF-κB signaling

SF Ang, SM Moochhala, PA MacAry, M Bhatia - PloS one, 2011 - journals.plos.org
Hydrogen sulfide (H2S) has been shown to induce transient receptor potential vanilloid 1
(TRPV1)-mediated neurogenic inflammation in polymicrobial sepsis. However, endogenous …

Delayed treatment with sodium hydrosulfide improves regional blood flow and alleviates cecal ligation and puncture (CLP)-induced septic shock

A Ahmad, N Druzhyna, C Szabo - Shock, 2016 - journals.lww.com
Cecal ligation and puncture (CLP)-induced sepsis is a serious medical condition, caused by
a severe systemic infection resulting in a systemic inflammatory response. Recent studies …

Hydrogen sulfide up-regulates substance P in polymicrobial sepsis-associated lung injury

H Zhang, A Hegde, SW Ng, S Adhikari… - The Journal of …, 2007 - journals.aai.org
Hydrogen sulfide (H 2 S) has been shown to induce the activation of neurogenic
inflammation especially in normal airways and urinary bladder. However, whether …

Hydrogen sulfide is a novel mediator of lipopolysaccharide‐induced inflammation in the mouse

L Li, M Bhatia, YZ Zhu, YC Zhu, RD Ramnath… - The FASEB …, 2005 - Wiley Online Library
Hydrogen sulfide (H2S) is synthesized in the body from l‐cysteine by several enzymes
including cystathionine‐γ‐lyase (CSE). To date, there is little information about the potential …

[HTML][HTML] Anti-inflammatory effects of H2S during acute bacterial infection: a review

F Benedetti, S Curreli, S Krishnan, S Davinelli… - Journal of translational …, 2017 - Springer
Abstract Hydrogen sulfide (H 2 S), previously only considered a toxic environmental air
pollutant, is now increasingly recognized as an important signaling molecule able to …

[HTML][HTML] Hydrogen sulfide exerts anti-oxidative and anti-inflammatory effects in acute lung injury

KK Zimmermann, SG Spassov, KM Strosing, PM Ihle… - Inflammation, 2018 - Springer
Acute lung injury (ALI) caused by septic stimuli is still a major problem in critical care
patients. We have shown previously that hydrogen sulfide (H 2 S) mediates anti …