Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …

Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …

Cardiac hypertrophy and heart failure are major causes of morbidity and mortality in Western
societies. Many factors have been implicated in cardiac remodeling, including alterations in …

Recent studies call into question the necessity of hypertrophic growth of the heart as a
“compensatory” response to hemodynamic stress. These findings, coupled with recent …

Cardiac hypertrophy leads to heart failure, and both conditions can ultimately prove lethal.
Here, traditional and novel mechanisms relating hypertrophy and heart failure are described …

Ventricular hypertrophy is an ominous escalation of hemodynamically stressful conditions
such as hypertension and valve disease. The pathophysiology of hypertrophy is complex …

Cardiac hypertrophy can be defined as an increase in heart mass. Pathological cardiac
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …

▪ Abstract Cardiac hypertrophy is the heart's response to a variety of extrinsic and intrinsic
stimuli that impose increased biomechanical stress. While hypertrophy can eventually …

Myocardial hypertrophy is a response of cardiac muscle to altered conditions of
haemodynamic overload caused by a large number of physiological and pathological …

Heart failure is one of the leading causes of mortality in the western world and encompasses
a wide spectrum of cardiac pathologies. When the heart experiences extended periods of …