[HTML][HTML] Antibacterial prodrugs to overcome bacterial resistance
B Jubeh, Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
Bacterial resistance to present antibiotics is emerging at a high pace that makes the
development of new treatments a must. At the same time, the development of novel …
development of new treatments a must. At the same time, the development of novel …
[HTML][HTML] Drug repurposing as an alternative for the treatment of recalcitrant bacterial infections
A Rangel-Vega, LR Bernstein… - Frontiers in …, 2015 - frontiersin.org
Bacterial infection remains one of the leading causes of death worldwide, and the options for
treating such infections are decreasing, due the rise of antibiotic-resistant bacteria. The …
treating such infections are decreasing, due the rise of antibiotic-resistant bacteria. The …
Dual action-based approaches to antibacterial agents
JB Bremner, JI Ambrus… - Current medicinal …, 2007 - ingentaconnect.com
This review collates and analyses recent work done on dual action approaches to tackling
the mounting health problem of resistance by human pathogenic bacteria to antibacterial …
the mounting health problem of resistance by human pathogenic bacteria to antibacterial …
[HTML][HTML] Update on drug-repurposing: is it useful for tackling antimicrobial resistance?
Antimicrobial resistance (AMR) has been globally recognized as a threat to human health
and healthcare systems [1]. In fact, AMR is estimated to be responsible for over 700,000 …
and healthcare systems [1]. In fact, AMR is estimated to be responsible for over 700,000 …
[HTML][HTML] Drug repurposing for the treatment of bacterial and fungal infections
A Miró-Canturri, R Ayerbe-Algaba… - Frontiers in microbiology, 2019 - frontiersin.org
Multidrug-resistant (MDR) pathogens pose a well-recognized global health threat that
demands effective solutions; the situation is deemed a global priority by the World Health …
demands effective solutions; the situation is deemed a global priority by the World Health …
Drug repurposing for antimicrobial discovery
Antimicrobial resistance continues to be a public threat on a global scale. The ongoing need
to develop new antimicrobial drugs that are effective against multi-drug-resistant pathogens …
to develop new antimicrobial drugs that are effective against multi-drug-resistant pathogens …
Drug repurposing to overcome microbial resistance
J Jampilek - Drug Discovery Today, 2022 - Elsevier
Infections are a growing global threat, and the number of resistant species of microbial
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …
Recent drug-repurposing-driven advances in the discovery of novel antibiotics
Drug repurposing is a safe and successful pathway to speed up the novel drug discovery
and development processes compared with de novo drug discovery approaches. Drug …
and development processes compared with de novo drug discovery approaches. Drug …
Antibiotic adjuvants: make antibiotics great again!
H Douafer, V Andrieu, O Phanstiel IV… - Journal of medicinal …, 2019 - ACS Publications
Multiple approaches have been developed to combat bacterial resistance. However, the
combination of antibiotic resistance mechanisms by bacteria and the limited number of …
combination of antibiotic resistance mechanisms by bacteria and the limited number of …
[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …