Vitamin B12 (cobalamin) is an essential cofactor for two metabolic pathways. It is obtained
principally from food of animal origin. Cobalamin becomes bioavailable through a series of …

Hypercobalaminemia (high serum vitamin B12 levels) is a frequent and underestimated
anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, reflecting a …

Abstract Vitamin B 12 (B12; also known as cobalamin) is a B vitamin that has an important
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …

Vitamin B-12 is a cofactor for 2 enzymes. In the cytoplasm, methionine synthase requires
vitamin B-12 in the form of methylcobalamin and catalyzes the conversion of homocysteine …

Although cobalamin (vitamin B12) was isolated almost 60 years ago, its biochemical,
physiologic and neurologic effects remain incompletely defined. New observations suggest …

We represent an update on diagnosing and treatment of vitamin B12 deficiency. Vitamin B12
deficiency should be suspected in all patients with unexplained anaemia and/or …

Cobalamin (vitamin B12) is an essential nutrient derived exclusively from bacterial sources.
It is an essential cofactor for three known enzymatic reactions. Untreated deficiency, caused …

Background: The standard screening test for vitamin B12 deficiency, measurement of total
plasma vitamin B12, has limitations of sensitivity and specificity. Plasma vitamin B12 bound …

Vitamin B 12 deficiency is a common condition which can present with non-specific clinical
features, and in severe cases with neurological or haematological abnormalities. Although …

Although cobalamin (vitamin B 12) deficiency was described over a century ago, it is still
difficult to establish the correct diagnosis and prescribe the right treatment. Symptoms …