Phycocyanin stimulates ulcerative colitis healing via selective activation of cannabinoid receptor-2, intestinal mucosal healing, treg accumulation, and P38mapk/mk2 …

WH El-Maadawy, E Hafiz, H Okasha, NA Osman… - Life Sciences, 2022 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory condition that until this date, lacks curative
treatments. Previously, synthetic selective CB2 receptor (CB2R) agonists demonstrated …

Phycocyanin ameliorates colitis-associated colorectal cancer by regulating the gut microbiota and the IL-17 signaling pathway

D Pan, B Huang, Y Gan, C Gao, Y Liu, Z Tang - Marine drugs, 2022 - mdpi.com
Phycocyanin (PC) is a pigment-protein complex. It has been reported that PC exerts anti-
colorectal cancer activities, although the underlying mechanism has not been fully …

Phycocyanin-derived bioactive peptide PCP3 ameliorates lipopolysaccharide-induced small intestinal inflammation in murine intestinal organoids and mice through …

B Wu, H Cheng, X Li, Q Yang, W Zhang, S Hao… - Food Bioscience, 2024 - Elsevier
Phycocyanin, a type of marine-derived food pigment protein, has been reported to exhibit
multiple biological functions, while the function of its potential bioactive peptides is rarely …

Phycocyanin ameliorates mouse colitis via phycocyanobilin-dependent antioxidant and anti-inflammatory protection of the intestinal epithelial barrier

W Guo, M Zeng, S Zhu, S Li, Y Qian, H Wu - Food & function, 2022 - pubs.rsc.org
Phycocyanin is a typical microalgal active compound with antioxidant and anti-inflammatory
efficacy, and the pigment moiety phycocyanobilin has been recently proposed as its active …

Enocyanin alleviates experimental colitis and restores gut microbiota homeostasis as functional foods

C Li, Y Huang, M Qin, Q He, Z Lin, X Zhang, H Ren… - Food Bioscience, 2024 - Elsevier
Enocyanin is an anthocyanin-rich extract that comes from grape peels and is increasingly
considered a promising additive in the food industry. To date its functionality as a potential …

The alleviative effect of C-phycocyanin peptides against TNBS-induced inflammatory bowel disease in zebrafish via the MAPK/Nrf2 signaling pathways

F Xu, F Yang, Y Qiu, C Wang, Q Zou, L Wang… - Fish & Shellfish …, 2024 - Elsevier
Introduction Ulcerative colitis (UC) is an incurable and highly complex chronic inflammatory
bowel disease (IBD) affecting millions of people worldwide. C-phycocyanin (C-PC) has been …

Dietary quercetin ameliorates experimental colitis in mouse by remodeling the function of colonic macrophages via a heme oxygenase-1-dependent pathway

S Ju, Y Ge, P Li, X Tian, H Wang, X Zheng, S Ju - Cell cycle, 2018 - Taylor & Francis
Inflammatory bowel disease (IBD) results from a chronic intestinal inflammation and tissue
destruction via an aberrant immune-driven inflammatory response towards an altered gut …

Aureusidin derivative CNQX inhibits chronic colitis inflammation and mucosal barrier damage by targeting myeloid differentiation 2 protein

Y Yang, Y Sheng, J Wang, X Zhou… - Journal of Cellular …, 2021 - Wiley Online Library
Our previous study has found that aureusidin can inhibit inflammation by targeting myeloid
differentiation 2 (MD2) protein. Structural optimization of aureusidin gave rise to a derivative …

[HTML][HTML] Phillygenin attenuated colon inflammation and improved intestinal mucosal barrier in DSS-induced colitis mice via TLR4/Src mediated MAPK and NF-κB …

HH Xue, JJ Li, SF Li, J Guo, RP Yan, TG Chen… - International Journal of …, 2023 - mdpi.com
Ulcerative colitis (UC) is a chronic, relapsing, and nonspecific inflammatory bowel disease
(IBD). Phillygenin (PHI), a natural bioactive ingredient, isolated from Forsythiae Fructus …

p-Cymene and Rosmarinic Acid Ameliorate TNBS-Induced Intestinal Inflammation Upkeeping ZO-1 and MUC-2: Role of Antioxidant System and Immunomodulation

RO Formiga, EB Alves Júnior, RC Vasconcelos… - International journal of …, 2020 - mdpi.com
p-Cymene (pC) and rosmarinic acid (RA) are secondary metabolites that are present in
medicinal herbs and Mediterranean spices that have promising anti-inflammatory properties …