Renal disease is a major worldwide public health problem that affects one in ten people.
Renal failure is caused by the irreversible loss of the structural and functional units of kidney …

The kidney has the capacity to recover from ischemic and toxic insults. Although there has
been debate about the origin of cells that replace injured epithelial cells, it is now widely …

The kidney is widely regarded as an organ without regenerative abilities. However, in recent
years this dogma has been challenged on the basis of observations of kidney recovery …

The kidney has been considered a highly terminally differentiated organ of the body, and its
proliferative potential is low, with the result that it has been thought of as a most unlikely …

Significant advances have been made in stem cell research over the past decade. A number
of nonhematopoietic sources of stem cells (or progenitor cells) have been identified …

Renal damage resulting from acute and chronic kidney injury poses an important problem to
public health. Currently, patients with end-stage renal disease rely solely on kidney …

Given its complexity, high metabolic activity and excretory functions, the kidney is particularly
susceptible to acute ischemic and toxin-mediated injury. Current therapies do not facilitate …

End-stage renal disease and acute renal failure are the most important issues of practical
and clinical nephrology, bearing in mind their high mortality rate, solely symptomatic …

Potential use of stem or progenitor cells for kidney regeneration | Nature Reviews Nephrology
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The kidney has the capacity for regeneration and repair after a variety of insults. Over the
past few decades, factors that promote repair of the injured kidney have been extensively …