Main Factors Shaping Amino Acid Usage Across Evolution

G Lamolle, D Simón, A Iriarte, H Musto - Journal of Molecular Evolution, 2023 - Springer
The standard genetic code determines that in most species, including viruses, there are 20
amino acids that are coded by 61 codons, while the other three codons are stop triplets …

Protein evolution within and between species

AO Schmitt, J Schuchhardt, A Ludwig… - Journal of theoretical …, 2007 - Elsevier
Protein evolution can be seen as the successive replacement of amino acids by other amino
acids. In general, it is a very slow process which is triggered by point mutations in the …

Amino acid composition of genomes, lifestyles of organisms, and evolutionary trends: a global picture with correspondence analysis

F Tekaia, E Yeramian, B Dujon - Gene, 2002 - Elsevier
Can we infer the lifestyle of an organism from the characteristic properties of its genome?
More precisely, what are the relations between easily quantifiable properties from genomic …

[HTML][HTML] A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes

RD Knight, SJ Freeland, LF Landweber - Genome biology, 2001 - Springer
Background Correlations between genome composition (in terms of GC content) and usage
of particular codons and amino acids have been widely reported, but poorly explained. We …

Nucleotide bias causes a genomewide bias in the amino acid composition of proteins

GAC Singer, DA Hickey - Molecular biology and evolution, 2000 - academic.oup.com
We analyzed the nucleotide contents of several completely sequenced genomes, and we
show that nucleotide bias can have a dramatic effect on the amino acid composition of the …

Amino acid and codon usage profiles: adaptive changes in the frequency of amino acids and codons

H Goodarzi, N Torabi, HS Najafabadi, M Archetti - Gene, 2008 - Elsevier
In the work presented, the changes in codon and amino acid contents have been studied as
a function of environmental conditions by comparing pairs of homologs in a group of …

The trend of amino-acid gain is consistent with a doublet code

R Finkel, H Kohler - Current Proteomics, 2010 - ingentaconnect.com
The present-day genetic code, while universal, is not the result of a “frozen accident”, but
has evolved over time. Analysis of amino-acid frequency has recently identified amino acids …

Selection on synthesis cost affects interprotein amino acid usage in all three domains of life

J Swire - Journal of molecular evolution, 2007 - Springer
Most investigations of the forces shaping protein evolution have focussed on protein
function. However, cells are typically 50%–75% protein by dry weight, with protein …

Relationship between amino acid usage and amino acid evolution in primates

H Liu, Z Xie, S Tan, X Zhang, S Yang - Gene, 2015 - Elsevier
Amino acid usage varies from species to species. A previous study has found a universal
trend in amino acid gain and loss in many taxa and a one-way model of amino acid …

[PDF][PDF] Essential amino acid usage and evolutionary nutrigenomics of eukaryotes-insights into the differential usage of amino acids in protein domains and extra …

L Santana-Santos, F Prosdocimi… - Genetics and molecular …, 2008 - funpecrp.com.br
Nutrigenomics studies the effects of nutrients on the genome, transcriptome and proteome of
organisms, and here an evolutionary standpoint on this new discipline is presented. It is well …