Objectives: Beta-thalassemias are a group of recessively autosomal inherited disorders of
hemoglobin synthesis, which, due to mutations of the beta-globin gene, lead to various …

β‐thalassemia encompasses a group of monogenic diseases that have in common defective
synthesis of β‐globin. The defects involved are extremely heterogeneous and give rise to a …

Although advances in the care of patients with β-thalassemia translate into better patient
survival, this success has allowed previously unrecognized complications to emerge …

Improvement of survival in patients with β-thalassemia has allowed several clinical
morbidities to manifest, including renal complications. Patients may experience proximal …

The β-thalassemia syndromes reflect deficient or absent β-globin synthesis usually owing to
a mutation in the β-globin locus. The relative excess of α-globin results in the formation of …

The success that has been made in the care of patients with thalassemia has led to the
emergence of unrecognized complications including several renal abnormalities. Chronic …

β-thalassemia, a congenital genetic hematological disorder characterized by the decrease
or absence of β-globin chains, leads to a decrease in levels of Hemoglobin A. The affected …

Non-transfusion-dependent thalassemias include a variety of phenotypes that, unlike
patients with beta (β)-thalassemia major, do not require regular transfusion therapy for …

Thalassemia is a disease with an extensive morbidity profile affecting almost every organ
system. Renal involvement, once considered rare, is an underestimated and poorly studied …

Background Thalassemia is an inherited hematological disorder categorized by a decrease
or absence of one or more of the globin chains synthesis. Beta‐thalassemia is caused by …