Cells of the monocyte-macrophage lineage are targets for human immunodeficiency virus-1
(HIV-1) infection in vivo. However, many laboratory strains of HIV-1 that efficiently infect …

Laboratory isolates of human immunodeficiency virus type-1 (HIV-1) such as HTLV-IIIB are
generally T cell line-tropic and highly sensitive to neutralization by soluble CD4 (sCD4), a …

The V3 region of the human immunodeficiency virus type 1 (HIV-1) envelope protein is
known to have a major influence on macrophage tropism as well as the ability to cause …

Previous experiments indicate that the V3 hypervariable region of the human
immunodeficiency virus (HIV) envelope protein influences cell tropism of infection; however …

The V3 hypervariable region of the HIV-1 envelope protein is a major determinant of viral
tropism for macrophages. However, the replication of macrophage-tropic HIV-1 strains …

A functional analysis of chimeric proviral clones generated from the T-cell line-tropic isolate
HXB2 and the non-T-cell line-tropic isolate YU-2 identified the minimal determinant for …

Strains of human immunodeficiency virus type 1 differ in their abilities to infect and replicate
in primary human macrophages. Chimeric clones were constructed from a provirus unable …

In view of the current interest in in vivo murine models for acquired immunodeficiency
syndrome (AIDS), the interaction between human immunodeficiency virus type 1 (HIV-1) and …

An immunodominant determinant for cytotoxic T lymphocytes (CTLs) exists in the
hypervariable portion of human immunodeficiency virus-1 (HIV-1) gp160. Three mouse CTL …

Distinct sequences of human immunodeficiency virus type 1 (HIV-1) have been found
between different tissue compartments or subcompartments within a given tissue. Whether …