In the past two decades, many studies have shown that sine oculis homeobox 1 (Six1) is a
powerful regulator of organogenesis and disease, with important roles in tumorigenesis; …

Abstract Sineoculis homeobox homolog 1 (Six1), normally a developmentally restricted
transcriptional regulator, is frequently dysregulated in mutiple cancers. Increasing evidences …

Background Lung cancer is a common cancer and the leading cause of cancer-related
death worldwide. SIX3 is a human homologue of the highly conserved sine oculis gene …

The sineoculis homeobox homolog 1 (SIX1) protein has been found to be important for
cancer progression. However, its biological role in human endometrial carcinomas remains …

The Sineoculis homeobox homolog 1 (SIX1) protein has been found to be overexpressed in
several human cancers. However, its expression pattern and biological roles in esophageal …

Abstract Sineoculis homeobox homolog 1 (Six1) is one of the transcription factors that act as
master regulators of development and is frequently dysregulated in cancers. However, the …

Background: Many transcription factors involved in embryonic development and reactivated
in tumors are considered potential prognostic biomarkers and novel therapeutic targets in …

Sine oculis homeobox homologue 1 (SIX1) is a Six class homeobox gene conserved
throughout many species. It has been reported to act as an oncogene and is overexpressed …

Sine oculis homeobox homolog 1 (Six1) is crucial in normal organ development. Recently,
Six1 is reported to display aberrant expression in various cancers and plays important roles …

Abstract Sine Oculis Homeobox 1 (SIX1) is a member of homeobox transcription factor
family having pivotal roles in organismal development and differentiation. This protein …