Osteoporosis is a worldwide disease with a very high prevalence in humans older than 50.
The main clinical consequences are bone fractures, which often lead to patient disability or …

For early biomaterials, it was required to have a combination of physicochemical properties,
suitable to replace human body tissues and to be biologically inert. Since then a long way …

Osteoporosis (OP) is one of the most significant causes of morbidity, particularly in post-
menopausal women and older men. Despite its remarkable occurrence, the search for an …

Osteoporosis is caused by the disruption in homeostasis between bone formation and bone
resorption. Conventional management of osteoporosis involves systematic drug …

Biomaterial osteointegration depends not only on the properties of the implanted material
but also on the characteristics and regenerative capability of the host bone. For this reason …

Bone tissue has an astonishing self-healing capacity yet only for non-critical size defects (<
6 mm) and clinical intervention is needed for critical-size defects and beyond that along with …

The idea behind this introductory chapter is to help the reader to get a brief overview of
different biomaterials, devices, and their applications in various treatment options toward …

Since the second half of the 20th century, bioceramics are used for bone repair and
regeneration. Inspired by bones and teeth, and aimed at mimicking their structure and …

Bone substitute biomaterials are fundamental to the biomedical sector, and have recently
benefitted from extensive research and technological advances aimed at minimizing failure …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …