[HTML][HTML] Differentially expressed circRNAs in peripheral blood samples as potential biomarkers and therapeutic targets for acute angle-closure glaucoma

R Guan, S Angxiu, L Li, Z Kang, X Yan - Scientific reports, 2023 - nature.com
Glaucoma is the leading cause of irreversible blindness globally. Circular RNAs (circRNAs)
play vital roles in various biological processes as microRNA (miRNA) sponges and, thus …

[HTML][HTML] Targeting circular RNA-Glra2 alleviates retinal neurodegeneration induced by ocular hypertension

T Wang, S Li, XM Li, C Li, F Wang, Q Jiang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Glaucoma is a leading cause of irreversible vision loss characterized by retinal
neurodegeneration. Circular RNAs (circRNAs) have emerged as the potential biomarkers …

[HTML][HTML] Circular RNAs: novel promising biomarkers in ocular diseases

N Guo, X Liu, OP Pant, DD Zhou, J Hao… - International journal of …, 2019 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a novel class of endogenous non-coding RNAs produced by
back-splicing. They are found to be expressed in eukaryotic cells and play certain roles in …

[HTML][HTML] CircRNA is a rising star in researches of ocular diseases

C Zhang, J Hu, Y Yu - Frontiers in cell and developmental biology, 2020 - frontiersin.org
A newly rediscovered subclass of noncoding RNAs, circular RNAs (circRNAs), is produced
by a back-splicing mechanism with a covalently closed loop structure. They not only serve …

Integrative Analysis of miRNA and circRNA Expression Profiles and Interaction Network in HSV-1-Infected Primary Corneal Epithelial Cells

YH Cui, CQ Liu, XL Song, WZ Yi, Q Liu, J Liu… - Current Eye …, 2024 - Taylor & Francis
Abstract Purpose Circular RNAs (circRNAs) are products of alternative splicing with roles as
competitive endogenous RNAs or microRNA sponges, regulating gene expression and …

Genome-wide identification of circular RNAs as a novel class of putative biomarkers for an ocular surface disease

XM Li, HM Ge, J Yao, YF Zhou, MD Yao, C Liu… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: Pterygium is a common ocular surface disease with an unknown
etiology and threatens vision as it invades into the cornea. Circular RNAs (circRNAs) are a …

[HTML][HTML] Identification of circular RNA-Dcaf6 as a therapeutic target for optic nerve crush-induced RGC degeneration

Y Ji, J Li, S Liu, J Zhu, J Yao, K Li, B Yan - Genomics, 2024 - Elsevier
The death of retinal ganglion cells (RGCs) can cause irreversible injury in visual function.
Clarifying the mechanism of RGC degeneration is critical for the development of therapeutic …

[HTML][HTML] Circular RNA expression profiling identifies glaucoma-related circular RNAs in various chronic ocular hypertension rat models

X Chen, R Zhou, K Shan, Y Sun, B Yan, X Sun… - Frontiers in …, 2020 - frontiersin.org
Circular RNAs are characterized as a class of covalently closed circular RNA transcripts and
are associated with a variety of cellular processes and neurological diseases by sponging …

Comprehensive analysis of circRNA-Associated-ceRNA networks in human corneal endothelial dysfunction

J Qiu, K Shan, J Xiang, J Gu, R Zhou, X Zhang… - Cornea, 2022 - journals.lww.com
Purpose: Circular RNAs (circRNAs) are a novel class of endogenous noncoding RNAs that
regulate gene expression through the competitive endogenous RNA (ceRNA) mechanism …

Hsa_circ_0023826 protects against glaucoma by regulating miR-188-3p/MDM4 axis

B Qu, J Wang, Y Li, XW Wu… - Acta Biochimica …, 2023 - abp.ptbioch.edu.pl
Objective: Circular RNAs (circRNAs) are characterized as a class of covalently closed
circRNA transcripts and are associated with various cellular processes and neurological …