[HTML][HTML] Maintenance treatment of recurrent ovarian cancer: Is it ready for prime time?

P DiSilvestro, AA Secord - Cancer Treatment Reviews, 2018 - Elsevier
Approximately 1% of women in the United States will be diagnosed with epithelial ovarian
cancer (EOC) during their lifetime. It is most likely to present at a more advanced stage …

[HTML][HTML] Maintenance therapy for recurrent epithelial ovarian cancer: current therapies and future perspectives–a review

S Gupta, S Nag, S Aggarwal, A Rauthan… - Journal of ovarian …, 2019 - Springer
Epithelial ovarian cancer (EOC) is usually diagnosed late at an advanced stage. Though
EOC initially responds to treatment, the recurrence rate is pretty high. The efficacy of different …

Latest clinical evidence of maintenance therapy in ovarian cancer

CS Walsh - Current Opinion in Obstetrics and Gynecology, 2020 - journals.lww.com
Latest clinical evidence of maintenance therapy in ovarian c... : Current Opinion in Obstetrics
and Gynecology Latest clinical evidence of maintenance therapy in ovarian cancer : Current …

[HTML][HTML] Frontline maintenance treatment for ovarian cancer

O Elyashiv, YNS Wong, JA Ledermann - Current Oncology Reports, 2021 - Springer
Abstract Purpose of Review Advanced epithelial ovarian cancer remains the most lethal
gynaecological cancer. Most patients with advanced disease will relapse within 3 years after …

Frontline PARP inhibitor maintenance therapy in ovarian cancer: A Society of Gynecologic Oncology practice statement

B Pothuri, R O'Cearbhaill, R Eskander… - Gynecologic …, 2020 - Elsevier
PARP inhibitors (PARPi) have shown have activity in the treatment of ovarian cancer.
Previous studies documented activity in patients with germline (gBRCA) and tumor (tBRCA) …

Recurrent ovarian cancer: when and how to treat

M Hall, G Rustin - Current oncology reports, 2011 - Springer
Notwithstanding continuing efforts to improve the primary treatment for ovarian cancer, most
patients will ultimately develop recurrent disease. The benefits of detection and early …

Comparison of PARPis with angiogenesis inhibitors and chemotherapy for maintenance in ovarian cancer: a network meta-analysis

Y Feng, H Huang, T Wan, C Zhang, C Tong, J Liu - Advances in Therapy, 2019 - Springer
Introduction Seventy-five percent of ovarian cancer would relapse within 18–28 months after
platinum-base chemotherapy. Evidence suggests that maintenance chemotherapy is …

[HTML][HTML] Treatment of patients with recurrent epithelial ovarian cancer for whom platinum is still an option

M Buechel, TJ Herzog, SN Westin, RL Coleman… - Annals of …, 2019 - Elsevier
Background Ovarian cancer remains the most deadly gynecologic cancer with the majority
of patients relapsing within 3 years of diagnosis. Traditional treatment paradigms linked to …

Wanna get away? Maintenance treatments and chemotherapy holidays in gynecologic cancers

A Madariaga, GJS Rustin, RJ Buckanovich… - American Society of …, 2019 - ascopubs.org
Epithelial ovarian cancer has a very high rate of relapse after primary therapy; historically
approximately 70% of patients with a complete clinical response to surgery and adjuvant …

Therapeutic options following second-line platinum-based chemotherapy in patients with recurrent ovarian cancer: Comparison of active surveillance and …

I Ray-Coquard, MR Mirza, S Pignata, A Walther… - Cancer Treatment …, 2020 - Elsevier
Most women with advanced ovarian cancer respond to initial treatment, consisting of
surgical resection and≈ 6 cycles of platinum-based chemotherapy. However, disease …