Dysregulation of neuronal calcium homeostasis in Alzheimer's disease–A therapeutic opportunity?
Alzheimer's disease (AD) is the disease of lost memories. Synaptic loss is a major reason for
memory defects in AD. Signaling pathways involved in memory loss in AD are under intense …
memory defects in AD. Signaling pathways involved in memory loss in AD are under intense …
[HTML][HTML] Calcium signaling in Alzheimer's disease & therapies
Alzheimer's disease (AD) is the most common type of dementia and is characterized by the
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …
accumulation of amyloid (Aβ) plaques and neurofibrillary tangles in the brain. Much attention …
The dysregulation of intracellular calcium in Alzheimer disease
C Supnet, I Bezprozvanny - Cell calcium, 2010 - Elsevier
Alzheimer disease (AD) is the most common neurodegenerative disorder worldwide and is
at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD …
at present, incurable. The accumulation of toxic amyloid-beta (Aβ) peptide aggregates in AD …
Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities
JT Yu, RCC Chang, L Tan - Progress in neurobiology, 2009 - Elsevier
Calcium is involved in many facets of neuronal physiology, including activity, growth and
differentiation, synaptic plasticity, and learning and memory, as well as pathophysiology …
differentiation, synaptic plasticity, and learning and memory, as well as pathophysiology …
[HTML][HTML] Calcium dysregulation in Alzheimer's disease: a target for new drug development
Y Wang, Y Shi, H Wei - Journal of Alzheimer's disease & …, 2017 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a devastating neurodegenerative disorder and the most
common cause of dementia among aged people whose population is rapidly increasing. AD …
common cause of dementia among aged people whose population is rapidly increasing. AD …
[HTML][HTML] Role of calcium modulation in the pathophysiology and treatment of Alzheimer's disease
D Baracaldo-Santamaría, SS Avendaño-Lopez… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …
cause of progressive dementia in senior adults. It is characterized by memory loss and …
[HTML][HTML] Calcium dyshomeostasis in Alzheimer's disease pathogenesis
R Cascella, C Cecchi - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …
Ca2+ homeostasis dysregulation in Alzheimer's disease: a focus on plasma membrane and cell organelles
X Wang, W Zheng - The FASEB Journal, 2019 - Wiley Online Library
Emerging evidence indicates that Ca2+ is a vital factor in modulating the pathogenesis of
Alzheimer's disease (AD). In healthy neurons, Ca2+ concentration is balanced to maintain a …
Alzheimer's disease (AD). In healthy neurons, Ca2+ concentration is balanced to maintain a …
[HTML][HTML] Presenilin-dependent expression of STIM proteins and dysregulation of capacitative Ca2+ entry in familial Alzheimer's disease
L Bojarski, P Pomorski, A Szybinska, M Drab… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Mutations in presenilin 1 (PS1), which are the major cause of familial Alzheimer's disease
(FAD), are involved in perturbations of cellular Ca2+ homeostasis. Attenuation of …
(FAD), are involved in perturbations of cellular Ca2+ homeostasis. Attenuation of …
Intracellular calcium dysregulation: implications for Alzheimer's disease
S Magi, P Castaldo, ML Macrì… - BioMed research …, 2016 - Wiley Online Library
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …
neuronal loss. AD is associated with aberrant processing of the amyloid precursor protein …
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