The food contaminants nivalenol and deoxynivalenol induce inflammation in intestinal epithelial cells by regulating reactive oxygen species release
S Adesso, G Autore, A Quaroni, A Popolo, L Severino… - Nutrients, 2017 - mdpi.com
Fusarium mycotoxins are fungal metabolites whose ability to affect cereal grains as multi-
contaminants is progressively increasing. The trichothecene mycotoxins nivalenol (NIV) and …
contaminants is progressively increasing. The trichothecene mycotoxins nivalenol (NIV) and …
Co-exposure to low doses of the food contaminants deoxynivalenol and nivalenol has a synergistic inflammatory effect on intestinal explants
I Alassane-Kpembi, O Puel, P Pinton, AM Cossalter… - Archives of …, 2017 - Springer
The global incidence of Fusarium head blight and attendant cereal grains multi-
contamination by the trichothecene mycotoxins deoxynivalenol (DON) and nivalenol (NIV) …
contamination by the trichothecene mycotoxins deoxynivalenol (DON) and nivalenol (NIV) …
Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells
J Van De Walle, A During, N Piront, O Toussaint… - Toxicology in vitro, 2010 - Elsevier
The intake of deoxynivalenol (DON), a mycotoxin contaminating cereal food items, causes
gastro-intestinal illness in human and animal. This study investigated whether intracellular …
gastro-intestinal illness in human and animal. This study investigated whether intracellular …
Deoxynivalenol induces inflammation in IPEC-J2 cells by activating P38 Mapk and Erk1/2
H Zhang, X Deng, C Zhou, W Wu, H Zhang - Toxins, 2020 - mdpi.com
Fusarium-derived mycotoxin deoxynivalenol (DON) usually induces diarrhea, vomiting and
gastrointestinal inflammation. We studied the cytotoxic effect of DON on porcine small …
gastrointestinal inflammation. We studied the cytotoxic effect of DON on porcine small …
[HTML][HTML] Investigation of the inflammatory and oxidative stress-inducing effects of deoxynivalenol and T-2 toxin exposure in non-tumorigenic human intestinal cell …
JM Pomothy, O Szabó, ÁE Czimmermann, Á Babiczky… - Toxicon, 2021 - Elsevier
Fungi in the Fusarium genus produce trichothecene mycotoxins including deoxynivalenol
(DON) and T-2 toxin which may elicit their damaging effects on the gastrointestinal tract …
(DON) and T-2 toxin which may elicit their damaging effects on the gastrointestinal tract …
Nivalenol induces oxidative stress and increases deoxynivalenol pro-oxidant effect in intestinal epithelial cells
M Del Regno, S Adesso, A Popolo, A Quaroni… - Toxicology and applied …, 2015 - Elsevier
Mycotoxins are secondary fungal metabolites often found as contaminants in almost all
agricultural commodities worldwide, and the consumption of food or feed contaminated by …
agricultural commodities worldwide, and the consumption of food or feed contaminated by …
Mycotoxins nivalenol and deoxynivalenol differentially modulate cytokine mRNA expression in Jurkat T cells
Deoxynivalenol (DON) and its hydroxylated form nivalenol (NIV) are Fusarium mycotoxins
that occur in cereal grains alone or in combination. Several studies have shown that these …
that occur in cereal grains alone or in combination. Several studies have shown that these …
Effect of deoxynivalenol and other Type B trichothecenes on the intestine: a review
P Pinton, IP Oswald - Toxins, 2014 - mdpi.com
The natural food contaminants, mycotoxins, are regarded as an important risk factor for
human and animal health, as up to 25% of the world's crop production may be …
human and animal health, as up to 25% of the world's crop production may be …
Influence of deoxynivalenol on NF-κB activation and IL-8 secretion in human intestinal Caco-2 cells
J Van De Walle, B Romier, Y Larondelle, YJ Schneider - Toxicology Letters, 2008 - Elsevier
Deoxynivalenol (DON) is the most prevalent trichothecene mycotoxin in crops in Europe and
North America. In human intestinal Caco-2 cells, DON activates the mitogen-activated …
North America. In human intestinal Caco-2 cells, DON activates the mitogen-activated …
The food-associated ribotoxin deoxynivalenol modulates inducible NO synthase in human intestinal cell model
F Graziani, A Pujol, C Nicoletti, P Pinton… - Toxicological …, 2015 - academic.oup.com
The intestinal epithelium possesses active immune functions including the production of
proinflammatory cytokines and antimicrobial molecules such as nitric oxide (NO). As …
proinflammatory cytokines and antimicrobial molecules such as nitric oxide (NO). As …