ContextOver the last 2 decades, many new pharmacological agents have been introduced
to reduce the growing morbidity associated with asthma, but the long-term effects of these …

Objective To determine the comparative effectiveness and safety of current maintenance
strategies in preventing exacerbations of asthma. Design Systematic review and network …

Asthma exacerbations are major contributors to disease morbidity in patients of all ages. To
develop strategies that reduce the disease burden from exacerbations, it is helpful to review …

Background Asthma is a prevalent disease characterized by chronic inflammatory changes
of the airway and marked by airway hyperresponsiveness, edema, and excess mucus …

Background: Long-acting β-agonists may increase the risk for fatal and nonfatal asthma
exacerbations. Purpose: To assess the risk for severe, life-threatening, or fatal asthma …

Despite international and national guidelines, poor asthma control remains an issue.
Asthma exacerbations are costly to both the individual, and the healthcare provider …

BACKGROUND: Safety of long-acting beta agonists (LABA) has been questioned and
recent evidence suggested a detrimental effect on asthma control as well as an increased …

The stepwise approach to pharmacological treatment in adult asthma mandates that asthma
treatment is progressively stepped up to achieve symptom control and reduce the risk of …

Several current guidelines/strategies outline a treatment approach to asthma, which
primarily consider the goals of improving lung function and quality of life and reducing …

Background Patients who continue to experience asthma symptoms despite taking regular
inhaled corticosteroids (ICS) represent a management challenge. Leukotriene receptor …