Background: Implementing 1-hour and 3-hour sepsis bundles for patients presenting with
bacteraemia to public hospital emergency departments in the State of Queensland resulted …

Background Sepsis bundles, promulgated by Surviving Sepsis Campaign have not been
widely adopted because of variability in sepsis identification strategies, implementation …

Objective To determine if the introduction of an emergency department (ED) sepsis
screening tool and management bundle affects antibiotic prescribing and use. Design …

Problem: Sepsis is the leading cause of morbidity and mortality and antibiotic administration
within 60-minutes is a priority. The purpose of this quality improvement project was to …

Background Guidelines recommend initiation of appropriate antimicrobial therapy within 1 h
of severe sepsis diagnosis. Few sepsis bundles exist in the literature emphasizing initiation …

In this issue of the journal, Cressman et al describe the antibiotic coverage thresholds that
clinicians are willing to accept for the treatment of patients with sepsis of varying disease …

Objectives: We sought to systematically review and meta-analyze the available data on the
association between timing of antibiotic administration and mortality in severe sepsis and …

Background Current sepsis guidelines recommend administration of antibiotics within 1 hour
of emergency department (ED) triage. However, the quality of the supporting evidence is …

Abstract Objectives The Centers for Medicare and Medicaid Services Severe Sepsis and
Septic Shock Management Bundle (SEP‐1) assesses antibiotic administration, lactate …

This study evaluated 421 patients with fluid-refractory severe sepsis or septic shock. The
overall median time to antibiotics for these patients was 118 minutes, with times ranging …