We tested the hypothesis that high-viscosity (HV) plasma in extreme hemodilution causes
wall shear stress to be greater than low-viscosity (LV) plasma, leading to enhanced …

Increased plasma and blood viscosity are usually associated with pathological conditions;
however there are several situations in which the elevation of both parameters results in …

Hematocrit (Hct) of awake hamsters and CD-1 mice was acutely increased by isovolemic
exchange transfusion of packed red blood cells (RBCs) to assess the relation between Hct …

The endothelium-derived nitric oxide (NO) is one of the mediators of smooth muscle (SM)
relaxation. The release of NO by endothelium depends on the wall shear stress (WSS) to …

Effect of increasing blood viscosity during extreme hemodilution on capillary perfusion and
tissue oxygenation was investigated in the awake hamster skinfold model. Two isovolemic …

The circulation is adapted to specific levels of blood viscosity resulting in a balance that
simultaneously sets peripheral vascular resistance, blood pressure and cardiac output …

Background—It has been proposed that flow-mediated shear stress regulates vascular tone;
however, whether this operates in the human microcirculation is unknown. This study was …

We studied whether a flow-independent increase of luminal wall shear stress (WSS) could
dilate hamster arterioles in vivo and which endothelial mediators are potentially involved. To …

Increasing blood and plasma viscosity is generally associated with pathological conditions,
and increased cardiovascular risk, a perception based in part on studies where blood …

Endothelial function is modulated by wall shear stress acting on the vessel wall, which is
determined by fluid velocity and the local viscosity near the vessel wall. Red blood cell …