Mechanisms of cancer cachexia
MJ Tisdale - Physiological reviews, 2009 - journals.physiology.org
Up to 50% of cancer patients suffer from a progressive atrophy of adipose tissue and
skeletal muscle, called cachexia, resulting in weight loss, a reduced quality of life, and a …
skeletal muscle, called cachexia, resulting in weight loss, a reduced quality of life, and a …
[HTML][HTML] Molecular pathways leading to cancer cachexia
MJ Tisdale - Physiology, 2005 - journals.physiology.org
Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent
studies have suggested that both tumor and host factors play a major role in tissue …
studies have suggested that both tumor and host factors play a major role in tissue …
Cancer cachexia: metabolic alterations and clinical manifestations
MJ Tisdale - Nutrition, 1997 - Elsevier
Progressive wasting is common in many types of cancer and is one of the most important
factors leading to the early death of cancer patients. Although anorexia frequently …
factors leading to the early death of cancer patients. Although anorexia frequently …
Mechanisms mediating cancer cachexia
D Toomey, HP Redmond, D Bouchier‐Hayes - Cancer, 1995 - Wiley Online Library
Background. Cancer cachexia encompasses a wide range of metabolic, hormonal, and
cytokine‐related abnormalities that result in a wasting syndrome possibly accounting for up …
cytokine‐related abnormalities that result in a wasting syndrome possibly accounting for up …
[HTML][HTML] Cancer cachexia and related metabolic dysfunction
GWP Fonseca, J Farkas, E Dora… - International journal of …, 2020 - mdpi.com
Cancer cachexia is a complex multifactorial syndrome marked by a continuous depletion of
skeletal muscle mass associated, in some cases, with a reduction in fat mass. It is …
skeletal muscle mass associated, in some cases, with a reduction in fat mass. It is …
Advances in cancer cachexia: Intersection between affected organs, mediators, and pharmacological interventions
Advanced cancer patients exhibit cachexia, a condition characterized by a significant
reduction in the body weight predominantly from loss of skeletal muscle and adipose tissue …
reduction in the body weight predominantly from loss of skeletal muscle and adipose tissue …
Cancer cachexia
JA Norton, JL Peacock, SD Morrison… - Critical reviews in oncology …, 1987 - Elsevier
Cancer cachexia is a complex syndrome that includes host tissue wasting, anorexia,
asthenia, and abnormal host intermediary metabolism. It is present in approximately 50% of …
asthenia, and abnormal host intermediary metabolism. It is present in approximately 50% of …
Cancer cachexia: understanding the molecular basis
JM Argilés, S Busquets, B Stemmler… - Nature Reviews …, 2014 - nature.com
Cancer cachexia is a devastating, multifactorial and often irreversible syndrome that affects
around 50–80% of cancer patients, depending on the tumour type, and that leads to …
around 50–80% of cancer patients, depending on the tumour type, and that leads to …
Mechanisms of metabolic dysfunction in cancer-associated cachexia
M Petruzzelli, EF Wagner - Genes & development, 2016 - genesdev.cshlp.org
Metabolic dysfunction contributes to the clinical deterioration observed in advanced cancer
patients and is characterized by weight loss, skeletal muscle wasting, and atrophy of the …
patients and is characterized by weight loss, skeletal muscle wasting, and atrophy of the …
Cancer cachexia
MJ Tisdale - Langenbeck's Archives of Surgery, 2004 - Springer
Causative factors Nutritional supplementation or pharmacological manipulation of appetite
are unable to control the muscle atrophy seen in cancer cachexia. This suggests that tumour …
are unable to control the muscle atrophy seen in cancer cachexia. This suggests that tumour …