[HTML][HTML] Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications

V Sundararajan, FH Sarkar, TS Ramasamy - Cellular Oncology, 2018 - Springer
Background Recent advances in cancer biology have highlighted the relevance of
exosomes and nanovesicles as carriers of genetic and biological messages between cancer …

Exosome-mediated remodeling of the tumor microenvironment: from local to distant intercellular communication

Y Huang, M Kanada, J Ye, Y Deng, Q He, Z Lei… - Cancer Letters, 2022 - Elsevier
Extracellular vesicles (EVs) are membrane-enveloped nanoscale particles that carry various
bioactive signaling molecules secreted by cells. Their biological roles depend on the …

[HTML][HTML] Functions and therapeutic roles of exosomes in cancer

JA Tickner, AJ Urquhart, SA Stephenson… - Frontiers in …, 2014 - frontiersin.org
The role of exosomes in cancer development has become the focus of much research, due
to the many emerging roles possessed by exosomes. These micro-vesicles that are …

Exosomes in tumor microenvironment influence cancer progression and metastasis

C Kahlert, R Kalluri - Journal of molecular medicine, 2013 - Springer
Exosomes are small membrane vesicles of endocytic origin with a size of 50–100 nm. They
can contain microRNAs, mRNAs, DNA fragments, and proteins, which are shuttled from a …

[HTML][HTML] Tumor exosomes: a double-edged sword in cancer therapy

W Sun, J Luo, H Jiang, DD Duan - Acta Pharmacologica Sinica, 2018 - nature.com
Tumor cells produce and secrete more nucleic acids, proteins and lipids than normal cells.
These molecules are transported in the blood or around the cells in membrane …

[HTML][HTML] Exosomes and their role in cancer progression

Y Liu, K Shi, Y Chen, X Wu, Z Chen, K Cao… - Frontiers in …, 2021 - frontiersin.org
Exosomes from extracellular vesicles can activate or inhibit various signaling pathways by
transporting proteins, lipids, nucleic acids and other substances to recipient cells. In …

[HTML][HTML] Tumor-derived exosomes in cancer progression and treatment failure

S Yu, H Cao, B Shen, J Feng - Oncotarget, 2015 - ncbi.nlm.nih.gov
Exosomes have diameter within the range of 30-100nm and spherical to cup-shaped
nanoparticles with specific surface molecular characteristics, such as CD9 and CD63. These …

[HTML][HTML] Exosomes: New players in cancer

W Guo, Y Gao, N Li, F Shao… - Oncology …, 2017 - … .spandidos-publications.com
The past decade has witnessed an exponential increase in research on exosomes. For
many years considered to be extracellular debris, exosomes are now considered important …

Exosome: Function and role in cancer metastasis and drug resistance

C Zhang, Q Ji, Y Yang, Q Li… - Technology in cancer …, 2018 - journals.sagepub.com
As a kind of nanometric lipidic vesicles, exosomes have been presumed to play a leading
role in the regulation of tumor microenvironment through exosomes-mediated transfer of …