Demethoxycurcumin induces apoptosis in HER2 overexpressing bladder cancer cells through degradation of HER2 and inhibiting the PI3K/Akt pathway

CC Kao, YC Cheng, MH Yang, TL Cha… - Environmental …, 2021 - Wiley Online Library
Bladder cancer is the most common malignancy of the urinary tract and arising from the
epithelial lining of the urinary bladder. Resistance to cytotoxic therapies is associated with …

[HTML][HTML] Antitumor effects of curcumin in human bladder cancer in vitro

J Shi, X Zhang, T Shi, H Li - Oncology Letters, 2017 - spandidos-publications.com
Bladder cancer is one of the major causes of cancer‑associated mortality, with a high
incidence. Curcumin, a polyphenol compound extracted from turmeric, has been identified to …

[HTML][HTML] Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2

BH Park, JE Lim, HG Jeon, SI Seo, HM Lee, HY Choi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Resistance of bladder cancer to cisplatin is a major obstacle to successful treatment. In the
current study, we investigated the apoptotic effects of curcumin and cisplatin co-treatment in …

[HTML][HTML] Curcumin induces apoptosis in EJ bladder cancer cells via modulating C-Myc and PI3K/Akt signaling pathway

J Wang, Z Wang, H Wang, J Zhao… - World Journal of …, 2011 - ncbi.nlm.nih.gov
Background Cancer chemopreventive agent curcumin has been shown to possess cell
growth inhibition and apoptosis induction properties in several types of cancer. However, the …

Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-κB and nuclear factor-κB–regulated …

AM Kamat, G Sethi, BB Aggarwal - Molecular cancer therapeutics, 2007 - AACR
Bladder cancer mortality varies between the countries; whereas being highest in Western
countries, it is lowest in Eastern countries, such as India. Cigarette smoking is one of the …

Curcumin reverses benzidine-induced cell proliferation by suppressing ERK1/2 pathway in human bladder cancer T24 cells

X Sun, QF Deng, ZF Liang, ZQ Zhang, L Zhao… - Experimental and …, 2016 - Elsevier
Bladder cancer is one of the leading causes of cancer-related death in the world. Prolonged
exposure to benzidine is a known cause of bladder cancer. Curcumin has been clinically …

RETRACTED: Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and …

ST Tharakan, T Inamoto, B Sung, BB Aggarwal… - 2010 - Elsevier
Little progress has been made in the last three decades in the treatment of bladder cancer.
Novel agents that are nontoxic and can improve the current standard of care of this disease …

Antiproliferative and apoptosis-inducing activity of curcumin against human gallbladder adenocarcinoma cells

M Ono, T Higuchi, M Takeshima, C Chen… - Anticancer …, 2013 - ar.iiarjournals.org
Aim: Curcumin has potent antitumor activity against many types of human cancers. However,
the inhibitory effects and possible mechanisms of curcumin on gallbladder cancer remains …

Curcumin modulates MicroRNA-203–mediated regulation of the Src-Akt axis in bladder cancer

S Saini, S Arora, S Majid, V Shahryari, Y Chen… - Cancer prevention …, 2011 - AACR
Bladder cancer is often associated with recurrence and progression to invasive metastatic
disease that have palliative therapeutic options. The use of traditional chemotherapeutic …

Curcumin inhibits bladder cancer progression via regulation of β-catenin expression

J Shi, Y Wang, Z Jia, Y Gao, C Zhao, Y Yao - Tumor Biology, 2017 - journals.sagepub.com
Bladder cancer has a considerable morbidity and mortality impact with particularly poor
prognosis. Curcumin has been recently noticed as a polyphenolic compound separated …