[HTML][HTML] Defining therapeutic targets for renal fibrosis: Exploiting the biology of pathogenesis

H Yan, J Xu, Z Xu, B Yang, P Luo, Q He - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Renal fibrosis is a failed wound-healing process of the kidney tissue after chronic, sustained
injury, which is a common pathway and pathological marker of virtually every type of chronic …

Cellular and molecular mechanisms of kidney fibrosis

S Djudjaj, P Boor - Molecular aspects of medicine, 2019 - Elsevier
Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …

[图书][B] Renal Fibrosis: Mechanisms and Therapies

BC Liu, HY Lan, LL Lv - 2019 - Springer
The high prevalence of chronic kidney disease (CKD) is a tremendous global burden. In
developed countries, it is estimated that more than 10% of adults present with various …

Cellular orchestrators of renal fibrosis

B Conway, J Hughes - QJM: An International Journal of …, 2012 - academic.oup.com
Renal fibrosis is a key determinant of the progression of many renal diseases and
represents a final common pathway that adversely affects outcome. The evolution of renal …

Cellular and molecular mechanisms of renal fibrosis

Y Liu - Nature Reviews Nephrology, 2011 - nature.com
Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost
all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of …

Cellular and molecular pathways that lead to progression and regression of renal fibrogenesis

H Okada, R Kalluri - Current molecular medicine, 2005 - ingentaconnect.com
Renal fibrosis is a common consequence and often a central feature of all the progressive
renal diseases that lead to end-stage renal failure. In comparison to wound healing, during …

Renal fibrosis: novel insights into mechanisms and therapeutic targets

P Boor, T Ostendorf, J Floege - Nature Reviews Nephrology, 2010 - nature.com
Renal fibrosis is the common end point of virtually all progressive kidney diseases. Renal
fibrosis should not be viewed as a simple and uniform'scar', but rather as a dynamic system …

[HTML][HTML] Kidney fibrosis: from mechanisms to therapeutic medicines

R Huang, P Fu, L Ma - Signal Transduction and Targeted Therapy, 2023 - nature.com
Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …

[引用][C] Possible mechanisms of renal fibrosis

H Okada, F Strutz, TM Danoff, R Kalluri… - Progression of chronic …, 1996 - karger.com
Renal fibrosis is the final common pathway for nearly all forms of kidney disease that
progress towards end-stage renal failure. As a sequel of inflammation and injury, humoral …

Pathophysiological mechanisms of renal fibrosis: a review of animal models and therapeutic strategies

A Nogueira, MJ Pires, PA Oliveira - In vivo, 2017 - iv.iiarjournals.org
Chronic kidney disease (CKD) is a long-term condition in which the kidneys do not work
correctly. It has a high prevalence and represents a serious hazard to human health and …