In patients with septic shock, the administration of fluids during initial hemodynamic
resuscitation remains a major therapeutic challenge. We are faced with many open …

BACKGROUND IV fluid represents a basic therapeutic intervention for septic shock.
Unfortunately, the optimal administration of IV fluid to maximize patient outcomes and …

Among critically ill adults, sepsis remains both common and lethal. In addition to antibiotics
and source control, fluid resuscitation is a fundamental sepsis therapy. The physiology of …

Fluid infusion may be lifesaving in patients with severe sepsis, especially in the earliest
phases of treatment. Following initial resuscitation, however, fluid boluses often fail to …

Prompt intravenous fluid therapy is a fundamental treatment for patients with septic shock.
However, the optimal approach for administering intravenous fluid in septic shock …

Purpose: To determine whether progressively increasing fluid balance after initial fluid
resuscitation for septic shock is associated with increased mortality. Methods: A …

Fluid therapy, which is provided to restore and maintain tissue perfusion, is part of routine
management for almost all critically ill patients. However, because either too much or too …

Importance Approximately 20% to 30% of patients admitted to an intensive care unit have
sepsis. While fluid therapy typically begins in the emergency department, intravenous fluids …

Large volume fluid resuscitation is currently viewed as the cornerstone of the treatment of
septic shock. The surviving sepsis campaign (SSC) guidelines provide a strong …

In critically ill patients, fluid balance management is an integral part of the process of care. In
patients in shock or severe sepsis, aggressive initial fluid resuscitation has been shown to …