The determination of tissue‐specific DNA methylation patterns in forensic biofluids using bisulfite modification and pyrosequencing
T Madi, K Balamurugan, R Bombardi… - …, 2012 - Wiley Online Library
The goal of this study is to explore the application of epigenetic markers in the identification
of biofluids that are commonly found at the crime scene. A series of genetic loci were …
of biofluids that are commonly found at the crime scene. A series of genetic loci were …
Novel identification of biofluids using a multiplex methylation-specific PCR combined with single-base extension system
YC Lin, LC Tsai, JCI Lee, KL Liu, JTC Tzen… - … Science, Medicine, and …, 2016 - Springer
Purpose Knowledge of the composition of complex body fluid mixtures may aid forensic
investigations greatly. However, many of the traditional tests are presumptive in nature and …
investigations greatly. However, many of the traditional tests are presumptive in nature and …
Discovery of potential DNA methylation markers for forensic tissue identification using bisulphite pyrosequencing
A Vidaki, F Giangasparo… - Electrophoresis, 2016 - Wiley Online Library
The presence of specific body fluids at crime scenes could be linked with particular types of
crime, therefore attributing a DNA profile to a specific tissue could increase the evidential …
crime, therefore attributing a DNA profile to a specific tissue could increase the evidential …
Developmental validation studies of epigenetic DNA methylation markers for the detection of blood, semen and saliva samples
DSBS Silva, J Antunes, K Balamurugan… - Forensic Science …, 2016 - Elsevier
Determining the type and origin of body fluids in a forensic investigation can provide
important assistance in reconstructing crime scenes. A set of epigenetic markers, ZC3H12D …
important assistance in reconstructing crime scenes. A set of epigenetic markers, ZC3H12D …
Novel identification of biofluids using a multiplex methylation sensitive restriction enzyme-PCR system
YC Lin, LC Tsai, JCI Lee, CW Su, JTC Tzen… - Forensic Science …, 2016 - Elsevier
The identification of a specific body fluid encountered in a forensic investigation can give
crucial information. This identification can be aided by methylation profiles based on …
crucial information. This identification can be aided by methylation profiles based on …
Development of a body fluid identification multiplex via DNA methylation analysis
The goal of this study is to develop an epigenetic multiplex for body fluid identification based
on tissue specific DNA methylation. A series of genetic loci capable of discerning the origin …
on tissue specific DNA methylation. A series of genetic loci capable of discerning the origin …
Genome-wide methylation profiling and a multiplex construction for the identification of body fluids using epigenetic markers
HY Lee, JH An, SE Jung, YN Oh, EY Lee, A Choi… - Forensic Science …, 2015 - Elsevier
The identification of body fluids found at crime scenes can contribute to solving crimes by
providing important insights into crime scene reconstruction. In the present study, body fluid …
providing important insights into crime scene reconstruction. In the present study, body fluid …
Identification of body fluid-specific DNA methylation markers for use in forensic science
JL Park, OH Kwon, JH Kim, HS Yoo, HC Lee… - Forensic Science …, 2014 - Elsevier
DNA methylation, which occurs at the 5′-position of the cytosine in CpG dinucleotides, has
great potential for forensic identification of body fluids, because tissue-specific patterns of …
great potential for forensic identification of body fluids, because tissue-specific patterns of …
Methylation markers for the identification of body fluids and tissues from forensic trace evidence
S Forat, B Huettel, R Reinhardt, R Fimmers, G Haidl… - PloS one, 2016 - journals.plos.org
The identification of body fluids is an essential tool for clarifying the course of events at a
criminal site. The analytical problem is the fact that the biological material has been very …
criminal site. The analytical problem is the fact that the biological material has been very …
Potential forensic application of DNA methylation profiling to body fluid identification
HY Lee, MJ Park, A Choi, JH An, WI Yang… - International journal of …, 2012 - Springer
DNA analysis of various body fluid stains at crime scenes facilitates the identification of
individuals but does not currently determine the type and origin of the biological material …
individuals but does not currently determine the type and origin of the biological material …