Virus‐based immunotherapy is a promising approach to treat tumor. Closely mimicking the
structure and sequential infection processes of natural viruses is highly desirable for …

Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the
inter-kingdom interaction and communication, but the effector components enclosed in the …

The innate immune system plays a key role in protecting the human body from tumors,
which, unfortunately, is largely counteracted by their immune‐suppression function. Such an …

Amalgamation of the reactive oxygen species (ROS)-responsive stimulus with nanoparticles
has gained considerable interest owing to their high tumor specificity. Hypoxia plays a …

Currently, limited photosensitizers possess the capacity to reverse tumor hypoxia and
reduce programmed death ligand-1 (PD-L1) and transforming growth factor-β (TGF-β) …

Immunotherapy has achieved revolutionary success in clinics, but it remains challenging for
treating hepatocellular carcinoma (HCC) characterized by high vascularization. Here, it is …

As a promising therapeutic strategy against cancer, immunotherapy faces critical
challenges, especially in solid tumors. Immune checkpoint blockade therapy, particularly …

The abundant extracellular matrix (ECM) in solid tumors causes limited drug penetration and
hypoxia‐mediated chemoresistance, which lead to poor chemotherapy outcomes. To solve …

Drug-free macromolecular therapeutics are promising alternatives to traditional drugs.
Nanomedicines with multiple organelles targeting can potentially increase the efficacy …

An efficient antitumor immune response relies on multiple cells-based process including
tumor cells-targeted immunogenicity increment, dendritic cells (DCs)-targeted vaccine …