Phosphate homeostasis involves several major organs that are the skeleton, the intestine,
the kidney, and parathyroid glands. Major regulators of phosphate homeostasis are …

Intracellular phosphate is critical for cellular processes such as signaling, nucleic acid
synthesis, and membrane function. Extracellular phosphate (Pi) is an important component …

Phosphate in both inorganic and organic form is essential for several functions in the body.
Plasma phosphate level is maintained by a complex interaction between intestinal …

Recent studies of inherited disorders of phosphate metabolism have shed new light on the
understanding of phosphate metabolism. Phosphate has important functions in the body and …

Phosphate is essential for growth and maintenance of the skeleton and for generating high-
energy phosphate compounds. Evolutionary adaptation to high dietary phosphorous in …

Phosphate is a key component of several physiologic pathways, such as skeletal
development, bone mineralization, membrane composition, nucleotide structure …

Phosphate plays a critical and diverse role in human physiology. In addition to its
importance in skeletal mineralization, it is essential for energy homeostasis, enzyme …

Inorganic phosphate is essential for skeletal mineralization and for multiple cellular
functions, including glycolysis, gluconeogenesis, DNA synthesis, RNA synthesis, cellular …

Regulation of phosphate homeostasis is critical for many biological processes, and both
hypophosphatemia and hyperphosphatemia can have adverse clinical consequences. Only …

Phosphate plays many essential roles in our body. To accomplish these functions, serum
phosphate needs to be maintained in a certain range. Serum phosphate level is regulated …