Human neuronal maturation comes of age: cellular mechanisms and species differences
JL Wallace, AA Pollen - Nature Reviews Neuroscience, 2024 - nature.com
The delayed and prolonged postmitotic maturation of human neurons, compared with
neurons from other species, may contribute to human-specific cognitive abilities and …
neurons from other species, may contribute to human-specific cognitive abilities and …
[HTML][HTML] Epigenetic control and manipulation of neuronal maturation timing
During brain development, the sequence of developmental steps and the underlying
transcriptional regulatory logic are largely conserved across species. However, the temporal …
transcriptional regulatory logic are largely conserved across species. However, the temporal …
Adult neurogenesis in mammals–a theme with many variations
L Bonfanti, P Peretto - European Journal of Neuroscience, 2011 - Wiley Online Library
Investigations of adult neurogenesis in recent years have revealed numerous differences
among mammalian species, reflecting the remarkable diversity in brain anatomy and …
among mammalian species, reflecting the remarkable diversity in brain anatomy and …
Activity dependency and aging in the regulation of adult neurogenesis
G Kempermann - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
Age and activity might be considered the two antagonistic key regulators of adult
neurogenesis. Adult neurogenesis decreases with age but remains present, albeit at a very …
neurogenesis. Adult neurogenesis decreases with age but remains present, albeit at a very …
[HTML][HTML] Searching for signatures of brain maturity: what are we searching for?
LH Somerville - Neuron, 2016 - cell.com
Evidence of continued neurobiological maturation through adolescence is increasingly
invoked in discussions of youth-focused policies. This should motivate neuroscientists to …
invoked in discussions of youth-focused policies. This should motivate neuroscientists to …
[HTML][HTML] Metabolic regulation of neurodifferentiation in the adult brain
C Maffezzini, J Calvo-Garrido, A Wredenberg… - Cellular and Molecular …, 2020 - Springer
Understanding the mechanisms behind neurodifferentiation in adults will be an important
milestone in our quest to identify treatment strategies for cognitive disorders observed during …
milestone in our quest to identify treatment strategies for cognitive disorders observed during …
[HTML][HTML] Mechanisms of hierarchical cortical maturation
T Chomiak, B Hu - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Cortical information processing is structurally and functionally organized into hierarchical
pathways, with primary sensory cortical regions providing modality specific information and …
pathways, with primary sensory cortical regions providing modality specific information and …
Neurogenesis in the developing and adult brain—similarities and key differences
M Götz, M Nakafuku, D Petrik - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Adult neurogenesis in the mammalian brain is often viewed as a continuation of
neurogenesis at earlier, developmental stages. Here, we will critically review the extent to …
neurogenesis at earlier, developmental stages. Here, we will critically review the extent to …
[HTML][HTML] Adult neurogenesis and gliogenesis: possible mechanisms for neurorestoration
The subgranular zone (SGZ) and subventricular zone (SVZ) are developmental remnants of
the germinal regions of the brain, hence they retain the ability to generate neuronal …
the germinal regions of the brain, hence they retain the ability to generate neuronal …
[HTML][HTML] How widespread are the “young” neurons of the mammalian brain?
M Ghibaudi, L Bonfanti - Frontiers in Neuroscience, 2022 - frontiersin.org
After the discovery of adult neurogenesis (stem cell-driven production of new neuronal
elements), it is conceivable to find young, undifferentiated neurons mixed with mature …
elements), it is conceivable to find young, undifferentiated neurons mixed with mature …