Role of cAMP modulator supplementations during oocyte in vitro maturation in domestic animals

GR Leal, CAS Monteiro, JMG Souza-Fabjan… - Animal reproduction …, 2018 - Elsevier
Cyclic adenosine monophosphate (cAMP) is an important molecule in signal transduction
within the cell, functioning as a second cell messenger of gonadotrophin stimulation. The …

Control of oocyte maturation

FC Landim-Alvarenga, RRD Maziero - Animal Reproduction, 2014 - repositorio.unesp.br
Oocyte maturation is a complex process involving nuclear and cytoplasmic maturation. The
nuclear maturation is a chromosomal segregation and the cytoplasmic maturation involves …

Effect of different levels of intracellular cAMP on the in vitro maturation of cattle oocytes and their subsequent development following in vitro fertilization

AM Luciano, P Pocar, E Milanesi… - Molecular …, 1999 - Wiley Online Library
Serum, gonadotrophins, growth factors, and steroid hormones stimulate the in vitro
maturation (IVM) of competent oocytes, acting, directly or indirectly, upon the adenylate …

Roles of cAMP in regulation of both MAP kinase and p34cdc2 kinase activity during meiotic progression, especially beyond the MI stage

M Shimada, T Terada - Molecular Reproduction and …, 2002 - Wiley Online Library
Time‐dependent changes in the level of adenosine cyclic AMP (cAMP) in porcine oocytes
during meiotic progression from the germinal vesicle stage (GV stage) to the metaphase II …

Role of intracellular cyclic adenosine 3′, 5′-monophosphate concentration and oocyte-cumulus cells communications on the acquisition of the developmental …

AM Luciano, S Modina, R Vassena… - Biology of …, 2004 - academic.oup.com
The present study was designed to address the physiological role played by cAMP on gap
junction (GJ) mediated communications between oocyte and cumulus cells during in vitro …

Effect of cyclic AMP on the isolated human oocyte—cumulus complex

J Törnell, T Hillensjö - Human Reproduction, 1993 - academic.oup.com
Cyclic AMP (cAMP) is one of the key regulators of the resumption of oocyte meiosis (oocyte
maturation) in several mammalian species. In this study we have examined the role for …

Regulation of sheep oocyte maturation using cAMP modulators

RD Rose, RB Gilchrist, JM Kelly, JG Thompson… - Theriogenology, 2013 - Elsevier
Physical removal of mammalian cumulus-oocyte complexes (COCs) from ovarian follicles
results in spontaneous resumption of meiosis, largely because of a decrease in cAMP …

Effect of adenylate cyclase stimulation on meiotic resumption and cyclic AMP content of zona-free and cumulus-enclosed bovine oocytes in vitro

S Bilodeau, MA Fortier, MA Sirard - Reproduction, 1993 - rep.bioscientifica.com
The effect of adenylate cyclase stimulation via the components of the enzyme on nuclear
maturation in bovine cumulus-enclosed and zona-free oocytes was examined. The …

Meiotic arrest maintained by cAMP during the initiation of maturation enhances meiotic potential and developmental competence and reduces polyspermy of IVM/IVF …

T Somfai, K Kikuchi, A Onishi, M Iwamoto, D Fuchimoto… - Zygote, 2003 - cambridge.org
We investigated effects of invasive adenylate cyclase (iAC), 3-isobutyl-1-methylxanthine
(IBMX) and dibutyryl cyclic AMP (dbcAMP) on porcine oocyte in vitro maturation (IVM), in …

cAMP modulation during sheep in vitro oocyte maturation delays progression of meiosis without affecting oocyte parthenogenetic developmental competence

M Buell, JL Chitwood, PJ Ross - Animal reproduction science, 2015 - Elsevier
Removal of oocytes from their natural inhibitory follicular environment results in
spontaneous resumption of meiosis independent of normal signaling events that occur in …