Reversible Dual Fluorescence-Lifetime Imaging of Mitochondrial GSH and Microviscosity: Real-Time Evaluation of Ferroptosis Status

SY Wang, YC Qu, N Shao, LY Niu… - Analytical Chemistry, 2024 - ACS Publications
Ferroptosis, as a new form of regulated cell death, is implicated in various physiological and
pathological processes. Developing a single probe for an independent analysis of multiple …

A triple-targeting fluorescent probe reveals the glutathione and viscosity crosstalk in mitochondria, endoplasmic reticulum, and nucleoli in cells during ferroptosis

LL Wang, Q Xu, YZ Xie, YR Zhang, MH Zheng… - Sensors and Actuators B …, 2024 - Elsevier
Ferroptosis, a recently termed cell death form, is featured by iron accumulation and lipid
peroxidation, which plays various roles in physiological and pathological processes such as …

Dual Ratio and Ultraprecision Quantification of Mitochondrial Viscosity in Ferroptosis Enabled by a Vibration-Based Triple-Emission Fluorescent Probe

L Li, Y Huang, X Jin, Q Wang, J Su, L Guo - Analytical Chemistry, 2023 - ACS Publications
Ferroptosis is a new mode of cell death with major morphological changes in mitochondria,
including structural shrinkage and increased membrane density, indicating the …

Fluorescent probes for ferroptosis bioimaging: advances, challenges, and prospects

J Yin, J Zhan, Q Hu, S Huang, W Lin - Chemical Society Reviews, 2023 - pubs.rsc.org
Ferroptosis is a form of regulatory cell death distinct from caspase-dependent apoptosis and
plays an important role in life entities. Since ferroptosis involves a variety of complex …

Unexpected dual-functional cyanine fluorophores: NIR multifunctional fluorescent probes for simultaneous monitoring of mitochondrial cysteine/viscosity during kidney …

Y Ye, M He, L Wang, XC Shen, H Chen - Sensors and Actuators B …, 2023 - Elsevier
Cysteine (Cys) level and mitochondrial viscosity are important factors controlling cellular
lipid peroxide metabolism and are closely related to ferroptosis. However, simultaneous …

[HTML][HTML] Near-infrared fluorescent probe for hydrogen sulfide: high-fidelity ferroptosis evaluation in vivo during stroke

T Liang, T Qiang, L Ren, F Cheng, B Wang, M Li… - Chemical …, 2022 - pubs.rsc.org
Ferroptosis is closely associated with cancer, neurodegenerative diseases and ischemia-
reperfusion injury and the detection of its pathological process is very important for early …

Dual-responsive fluorescent probe for imaging NAD (P) H and mitochondrial viscosity and its application in cancer cell ferroptosis

H Wei, Y Yu, G Wu, Y Wang, S Duan, J Han… - Sensors and Actuators B …, 2022 - Elsevier
Herein, we design and synthesize a dual-responsive fluorescent probe 3Q-2 and use it to
reveal the dynamic changes of NAD (P) H and mitochondrial viscosity during ferroptosis, a …

Real-time monitoring viscosity during ferroptosis with a novel mitochondria-specific fluorescent probe

F Zheng, J Ding, S Huang, A Bi, S Liu, K Zhang… - Dyes and …, 2023 - Elsevier
Ferroptosis is a form of regulated cell death that depends on iron and is associated with
various diseases. Recent studies have shown that mitochondria play a critical role in …

Recent advances in small-molecule fluorescent probes for studying ferroptosis

YL Qi, HR Wang, LL Chen, YT Duan… - Chemical Society …, 2022 - pubs.rsc.org
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …

Fluorescence imaging of intracellular glutathione levels in the endoplasmic reticulum to reveal the inhibition effect of rutin on ferroptosis

Q Chen, Y Wang, T Yue, H Wei, S Li… - Analytical …, 2023 - ACS Publications
Ferroptosis is an emerging form of nonapoptotic cell death, and the search for novel
ferroptosis inhibitors is of great importance to explore unique cytoprotective strategies …