Inflammatory Response and Immune Regulation in Brain‐Heart Interaction after Stroke

L Zou, R Han - Cardiovascular Therapeutics, 2022 - Wiley Online Library
Cerebrocardiac syndrome (CCS) is one of the secondary myocardial injuries after stroke.
Cerebrocardiac syndrome may result in a poor prognosis with high mortality. Understanding …

Inflammatory responses mediate brain–heart interaction after ischemic stroke in adult mice

T Yan, Z Chen, M Chopp, P Venkat… - Journal of Cerebral …, 2020 - journals.sagepub.com
Stroke induces cardiac dysfunction which increases post stroke mortality and morbidity
particularly in aging population. Here, we investigated the effects of inflammatory responses …

Brain–heart interaction: cardiac complications after stroke

Z Chen, P Venkat, D Seyfried, M Chopp, T Yan… - Circulation …, 2017 - Am Heart Assoc
Neurocardiology is an emerging specialty that addresses the interaction between the brain
and the heart, that is, the effects of cardiac injury on the brain and the effects of brain injury …

Interactions between the autonomic nervous system and the immune system after stroke

L Zhu, L Huang, A Le, TJ Wang, J Zhang… - Comprehensive …, 2011 - Wiley Online Library
Acute stroke is one of the leading causes of morbidity and mortality worldwide. Stroke‐
induced immune‐inflammatory response occurs in the perilesion areas and the periphery …

Spleen associated immune-response mediates brain-heart interaction after intracerebral hemorrhage

W Li, L Li, W Li, M Chopp, P Venkat, A Zacharek… - Experimental …, 2020 - Elsevier
Background and purpose Intracerebral hemorrhage (ICH) patients frequently encounter
cardiovascular complications which may contribute to increased mortality and poor long …

Immunological characterization of stroke-heart syndrome and identification of inflammatory therapeutic targets

J Zheng, Y Ma, X Guo, J Wu - Frontiers in Immunology, 2023 - frontiersin.org
Acute cardiac dysfunction caused by stroke-heart syndrome (SHS) is the second leading
cause of stroke-related death. The inflammatory response plays a significant role in the …

Acute heart failure after Reperfused ischemic stroke: association with systemic and cardiac inflammatory responses

L Vornholz, F Nienhaus, M Gliem, C Alter… - Frontiers in …, 2021 - frontiersin.org
Patients with acute ischemic stroke (AIS) present an increased incidence of systemic
inflammatory response syndrome and release of Troponin T coinciding with cardiac …

Stroke–heart syndrome: recent advances and challenges

JF Scheitz, LA Sposato, J Schulz‐Menger… - Journal of the …, 2022 - Am Heart Assoc
After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …

Myocardial inflammation predicts remodeling and neuroinflammation after myocardial infarction

JT Thackeray, HC Hupe, Y Wang, JP Bankstahl… - Journal of the American …, 2018 - jacc.org
Background: The local inflammatory tissue response after acute myocardial infarction (MI)
determines subsequent healing. Systemic interaction may induce neuroinflammation as a …

Stroke Related Brain–Heart Crosstalk: Pathophysiology, Clinical Implications, and Underlying Mechanisms

X Fan, J Cao, M Li, D Zhang, I El‐Battrawy… - Advanced …, 2024 - Wiley Online Library
The emergence of acute ischemic stroke (AIS) induced cardiovascular dysfunctions as a
bidirectional interaction has gained paramount importance in understanding the intricate …