Genetics and brain transcriptomics of completed suicide
Objective: The authors sought to study the transcriptomic and genomic features of completed
suicide by parsing the method chosen, to capture molecular correlates of the distinctive …
suicide by parsing the method chosen, to capture molecular correlates of the distinctive …
A pilot genome wide association and gene expression array study of suicide with and without major depression
H Galfalvy, G Zalsman, YY Huang… - The world journal of …, 2013 - Taylor & Francis
Objectives. Suicide is partly heritable but the responsible genes have not been identified.
We conducted a gene-centric, low coverage single nucleotide polymorphism (SNP) pilot …
We conducted a gene-centric, low coverage single nucleotide polymorphism (SNP) pilot …
[PDF][PDF] Transcriptome alterations in the prefrontal cortex of subjects with schizophrenia who committed suicide
To better understand the pathophysiological events associate with suicide in subjects with
schizophrenia, we performed a DNA microarray expression profiling of the frontal cortex of …
schizophrenia, we performed a DNA microarray expression profiling of the frontal cortex of …
Brain gene expression pattern of subjects with completed suicide and comorbid substance use disorder
Abstract Background/Aim: Although individuals with substance use disorder (SUD) are at
high risk of committing suicide, most studies of postmortem gene expression exclude …
high risk of committing suicide, most studies of postmortem gene expression exclude …
Suicide neurobiology
In this review, we examine the history of the neurobiology of suicide, as well as the genetics,
molecular and neurochemical findings in suicide research. Our analysis begins with a …
molecular and neurochemical findings in suicide research. Our analysis begins with a …
Suicide candidate genes associated with bipolar disorder and schizophrenia: an exploratory gene expression profiling analysis of post-mortem prefrontal cortex
S Kim, KH Choi, AF Baykiz, HK Gershenfeld - BMC genomics, 2007 - Springer
Background Suicide is an important and potentially preventable consequence of serious
mental disorders of unknown etiology. Gene expression profiling technology provides an …
mental disorders of unknown etiology. Gene expression profiling technology provides an …
Insights into suicide and depression
NH Kalin - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
The suffering, anguish, and psychological trauma that loved ones endure when losing a
family member to suicide is devastating, and for most people, unimaginable. As mental …
family member to suicide is devastating, and for most people, unimaginable. As mental …
A review and meta-analysis of gene expression profiles in suicide
IS Piras, MJ Huentelman, F Pinna, P Paribello… - European …, 2022 - Elsevier
Suicide claims over 800,000 deaths worldwide, making it a serious public health problem.
The etiopathophysiology of suicide remains unclear and is highly complex, and postmortem …
The etiopathophysiology of suicide remains unclear and is highly complex, and postmortem …
Genome-wide association study of suicide death and polygenic prediction of clinical antecedents
Objective: Death by suicide is a highly preventable yet growing worldwide health crisis. To
date, there has been a lack of adequately powered genomic studies of suicide, with no …
date, there has been a lack of adequately powered genomic studies of suicide, with no …
Epigenetic dysregulation in the prefrontal cortex of suicide completers
The epigenome is thought to mediate between genes and the environment, particularly in
response to adverse life experiences. Similar to other psychiatric diseases, the suicide …
response to adverse life experiences. Similar to other psychiatric diseases, the suicide …