Genetics and brain transcriptomics of completed suicide

G Punzi, G Ursini, Q Chen… - American journal of …, 2022 - Am Psychiatric Assoc
Objective: The authors sought to study the transcriptomic and genomic features of completed
suicide by parsing the method chosen, to capture molecular correlates of the distinctive …

A pilot genome wide association and gene expression array study of suicide with and without major depression

H Galfalvy, G Zalsman, YY Huang… - The world journal of …, 2013 - Taylor & Francis
Objectives. Suicide is partly heritable but the responsible genes have not been identified.
We conducted a gene-centric, low coverage single nucleotide polymorphism (SNP) pilot …

[PDF][PDF] Transcriptome alterations in the prefrontal cortex of subjects with schizophrenia who committed suicide

K Garbett, R Gal-Chis, G Gaszner, DA Lewis… - Neuropsychopharmacol …, 2008 - mppt.hu
To better understand the pathophysiological events associate with suicide in subjects with
schizophrenia, we performed a DNA microarray expression profiling of the frontal cortex of …

Brain gene expression pattern of subjects with completed suicide and comorbid substance use disorder

B Cabrera, N Monroy-Jaramillo, GR Fries… - Complex …, 2019 - karger.com
Abstract Background/Aim: Although individuals with substance use disorder (SUD) are at
high risk of committing suicide, most studies of postmortem gene expression exclude …

Suicide neurobiology

C Ernst, N Mechawar, G Turecki - Progress in neurobiology, 2009 - Elsevier
In this review, we examine the history of the neurobiology of suicide, as well as the genetics,
molecular and neurochemical findings in suicide research. Our analysis begins with a …

Suicide candidate genes associated with bipolar disorder and schizophrenia: an exploratory gene expression profiling analysis of post-mortem prefrontal cortex

S Kim, KH Choi, AF Baykiz, HK Gershenfeld - BMC genomics, 2007 - Springer
Background Suicide is an important and potentially preventable consequence of serious
mental disorders of unknown etiology. Gene expression profiling technology provides an …

Insights into suicide and depression

NH Kalin - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
The suffering, anguish, and psychological trauma that loved ones endure when losing a
family member to suicide is devastating, and for most people, unimaginable. As mental …

A review and meta-analysis of gene expression profiles in suicide

IS Piras, MJ Huentelman, F Pinna, P Paribello… - European …, 2022 - Elsevier
Suicide claims over 800,000 deaths worldwide, making it a serious public health problem.
The etiopathophysiology of suicide remains unclear and is highly complex, and postmortem …

Genome-wide association study of suicide death and polygenic prediction of clinical antecedents

AR Docherty, AA Shabalin, E DiBlasi… - American journal of …, 2020 - Am Psychiatric Assoc
Objective: Death by suicide is a highly preventable yet growing worldwide health crisis. To
date, there has been a lack of adequately powered genomic studies of suicide, with no …

Epigenetic dysregulation in the prefrontal cortex of suicide completers

E Schneider, N El Hajj, F Müller, B Navarro… - … and genome research, 2015 - karger.com
The epigenome is thought to mediate between genes and the environment, particularly in
response to adverse life experiences. Similar to other psychiatric diseases, the suicide …