LEF1 mediates osteoarthritis progression through circRNF121/miR-665/MYD88 axis via NF-кB signaling pathway
T Wang, Z Hao, C Liu, L Yuan, L Li, M Yin, Q Li… - Cell Death & …, 2020 - nature.com
Osteoarthritis (OA) is a joint disease that causes great pain to patients and imposes a
tremendous burden on the world's medical resources. Regulatory noncoding RNAs …
tremendous burden on the world's medical resources. Regulatory noncoding RNAs …
CircATRNL1 protects against osteoarthritis by targeting miR-153-3p and KLF5
KF Wang, ZW Shi, DM Dong - International Immunopharmacology, 2021 - Elsevier
Background Osteoarthritis (OA) is characterized by chondrocyte injury. Circular RNAs
(circRNAs) are involved in the pathogenesis of various diseases, including OA. The purpose …
(circRNAs) are involved in the pathogenesis of various diseases, including OA. The purpose …
Circular RNA-CDR1as acts as the sponge of microRNA-641 to promote osteoarthritis progression
W Zhang, C Zhang, C Hu, C Luo, B Zhong, X Yu - Journal of Inflammation, 2020 - Springer
Background The antisense cerebellar degenerative-related protein-1 (CDR1as) has been
identified as a sponge for several microRNAs. MiR-641 has been shown to be …
identified as a sponge for several microRNAs. MiR-641 has been shown to be …
CircRNA_0092516 regulates chondrocyte proliferation and apoptosis in osteoarthritis through the miR-337-3p/PTEN axis
Z Huang, W Ma, J Xiao, X Dai… - The journal of …, 2021 - academic.oup.com
The dysregulation of circular RNAs (circRNAs) has been identified in various human
diseases. Here, we probed into the potential mechanism of circRNA_0092516 in …
diseases. Here, we probed into the potential mechanism of circRNA_0092516 in …
Circular RNA-9119 protects IL-1β-treated chondrocytes from apoptosis in an osteoarthritis cell model by intercepting the microRNA-26a/PTEN axis
C Chen, P Yin, S Hu, X Sun, B Li - Life Sciences, 2020 - Elsevier
Aims Osteoarthritis (OA) is a common degenerative joint disease characterized by cartilage
degeneration and joint inflammation. As its pathogenesis remains unclear, there are no …
degeneration and joint inflammation. As its pathogenesis remains unclear, there are no …
CircRNA circ_SEC24A upregulates DNMT3A expression by sponging miR-26b-5p to aggravate osteoarthritis progression
Z Zhang, B Yang, S Zhou, J Wu - International Immunopharmacology, 2021 - Elsevier
Background Osteoarthritis (OA) is a chronic degenerative disease characterized by
degeneration and injury of articular cartilage. Circular RNA_SEC24A (circ_SEC24A; …
degeneration and injury of articular cartilage. Circular RNA_SEC24A (circ_SEC24A; …
Circular RNA circ_0008365 regulates SOX9 by targeting miR-338-3p to inhibit IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation
S Shuai, Q Cai, Y Ou - Journal of orthopaedic surgery and research, 2022 - Springer
Background Osteoarthritis (OA) is a chronic disease that involves chondrocyte injury and
dysfunction. CircRNAs participate in OA progression, but the roles of circRNAs in the …
dysfunction. CircRNAs participate in OA progression, but the roles of circRNAs in the …
Circ_0008956 contributes to IL-1β-induced osteoarthritis progression via miR-149-5p/NAMPT axis
S Fu, Q Fan, J Xu, S Yu, M Sun, Y Ji, D Liu - International …, 2021 - Elsevier
Circular RNAs (circRNAs) have been identified to involve in the pathophysiology of
osteoarthritis (OA). Herein, this study aimed to investigate the role and mechanisms …
osteoarthritis (OA). Herein, this study aimed to investigate the role and mechanisms …
CircSERPINE2 weakens IL-1β-caused apoptosis and extracellular matrix degradation of chondrocytes by regulating miR-495/TGFBR2 axis
Q Zhang, X Qiao, W Xia - Bioscience Reports, 2020 - portlandpress.com
The dysregulated circular RNAs (circRNAs) are relevant to the development of osteoarthritis
(OA). The circRNA serpin family E member 2 (circSERPINE2) is dysregulated in OA, while …
(OA). The circRNA serpin family E member 2 (circSERPINE2) is dysregulated in OA, while …
Circ_0043947 contributes to interleukin 1β-induced injury in chondrocytes by sponging miR-671-5p to up-regulate RTN3 expression in osteoarthritis pathology
M He, Z Jia, Y Wen, X Chen - Journal of Orthopaedic Surgery and …, 2022 - Springer
Objective Osteoarthritis (OA) is a chronic joint disease featured by articular cartilage
degeneration and damage. Accumulating evidence have demonstrated the pivotal …
degeneration and damage. Accumulating evidence have demonstrated the pivotal …