The role of extracellular vesicles in idiopathic pulmonary fibrosis progression: an approach on their therapeutics potential

AA Ramírez-Hernández, JM Velázquez-Enríquez… - Cells, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease of unknown etiology.
Different types of cells are involved in fibrogenesis, which is persistently physical and …

Extracellular vesicles in idiopathic pulmonary fibrosis: pathogenesis and therapeutics

Y Fujita - Inflammation and Regeneration, 2022 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease that occurs due to
increased fibrosis of lung tissue in response to chronic injury of the epithelium. Therapeutic …

[HTML][HTML] Proteomic analysis reveals key proteins in extracellular vesicles cargo associated with idiopathic pulmonary fibrosis in vitro

JM Velázquez-Enríquez, JC Santos-Álvarez… - Biomedicines, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, and highly fatal
disease. It is characterized by the increased activation of both fibroblast and myofibroblast …

Extracellular vesicles in pulmonary fibrosis models and biological fluids of interstitial lung disease patients: A scoping review

M d'Alessandro, L Bergantini, E Bargagli, S Vidal - Life, 2021 - mdpi.com
Introduction: Interstitial lung diseases (ILDs) are a heterogeneous group of diffuse
parenchymal lung disorders characterized by the pathogenetic involvement of interstitium …

Mesenchymal stem cell-derived extracellular vesicles as idiopathic pulmonary fibrosis microenvironment targeted delivery

L Sang, X Guo, H Fan, J Shi, S Hou, Q Lv - Cells, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) affects an increasing number of people globally, yet
treatment options remain limited. At present, conventional treatments depending on drug …

Increased extracellular vesicles mediate WNT5A signaling in idiopathic pulmonary fibrosis

A Martin-Medina, M Lehmann, O Burgy… - American journal of …, 2018 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease characterized by lung
epithelial cell injury, increased (myo) fibroblast activation, and extracellular matrix …

Role of mesenchymal stem cells and extracellular vesicles in idiopathic pulmonary fibrosis

S Kletukhina, G Mutallapova, A Titova… - International Journal of …, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial fibrotic disease that leads to
disability and death within 5 years of diagnosis. Pulmonary fibrosis is a disease with a …

Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk

T Kadota, Y Fujita, J Araya, N Watanabe… - Journal of …, 2021 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is characterized by devastating and progressive lung
parenchymal fibrosis, resulting in poor patient prognosis. An aberrant recapitulation of …

[HTML][HTML] Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis

O Burgy, CH Mayr, D Schenesse… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a lethal chronic lung disease characterized by aberrant
intercellular communication, extracellular matrix deposition, and destruction of functional …

Diagnostic and therapeutic applications of extracellular vesicles in interstitial lung diseases

A Ibrahim, A Ibrahim, T Parimon - Diagnostics, 2021 - mdpi.com
Interstitial lung diseases (ILDs) are chronic irreversible pulmonary conditions with significant
morbidity and mortality. Diagnostic approaches to ILDs are complex and multifactorial …