Background Breast cancer (BC), the second most common cause of cancer-related deaths,
remains a significant threat to the health and wellness of women worldwide. The tumor …

The tumor microenvironment (TME) is cellular environment in addition to harboring
carcinoma cells, consists of different components (eg, blood vessels, immune cells …

In recent years, it has been shown that breast cancer consists not only of neoplastic cells,
but also of significant alterations in the surrounding stroma or tumor microenvironment …

Simple Summary The tumor microenvironment (TME) in breast cancer plays important roles
in tumor behavior and treatment response, making its pathologic assessment critical for …

Breast cancer is presently the most predominant tumor type and the second leading cause
of tumor-related deaths among women. Although advancements in diagnosis and …

Therapy resistance or tumor relapse in cancer is common. Tumors develop resistance to
chemotherapeutic through a variety of mechanisms, with tumor microenvironment (TM) …

Breast cancer is a complex, dynamic disease that acquires heterogeneity through various
mechanisms, allowing cancer cells to proliferate, survive and metastasise. Heterogeneity is …

Introduction: Numerous clinical and pre-clinical studies have provided ample evidence
supporting that the tumor microenvironment plays a significant role during breast cancer …

Simple Summary The spread of breast cancer to distant parts of the body (metastasis) is the
major cause of death in breast cancer patients. Research has shown that apart from the …

The tumour microenvironment plays important roles in cancer initiation, growth, progression,
invasion and metastasis, yet the molecular basis underlying these tumour-promoting effects …