Population substructure within human populations is globally evident and a well-known
confounding factor in many genetic studies. In contrast, admixture mapping exploits …

The populations of Africa harbour the greatest human genetic diversity following an
evolutionary history tracing its beginnings on the continent to time before the emergence of …

As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

Exploring genomic studies in Africa | Genome Medicine Skip to main content SpringerLink
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Genomics in Africa: Avoiding Past Pitfalls: Cell Skip to Main Content Skip to Main Menu
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Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

Despite Africa's central role in the origin of our species, our knowledge of the genomic
diversity in Africa is remarkably sparse. A recent publication by Choudhury et al …

Human genetic studies have long been vastly Eurocentric, raising a key question about the
generalizability of these study findings to other populations. Because humans originated in …

Admixed populations present unique opportunities to discover the genetic factors underlying
many multifactorial diseases. The geographical position and complex history of South Africa …

The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it
remains vastly understudied. With biomedical research increasingly focused on human …