Only kosmotrope anions trigger fibrillization of the recombinant core spidroin eADF4(C16) from Araneus diadematus
Recombinant core spidroin eADF4 (C16) has received increasing attention due to its ability
to form micro‐and nano‐structured scaffolds, which are based on nanofibrils with great …
to form micro‐and nano‐structured scaffolds, which are based on nanofibrils with great …
Tyrosine Mutation in the Characteristic Motif of the Amorphous Region of Spidroin for Self-Assembly Capability Enhancement
Z Chen, C Cheng, L Liu, B Lin, Y Xiong, W Zhu… - ACS …, 2024 - ACS Publications
Spidroin, with robust mechanical performance and good biocompatibility, could fulfill broad
applications in material science and biomedical fields. Development of miniature spidroin …
applications in material science and biomedical fields. Development of miniature spidroin …
Wet-spinning synthetic fibers from aggregate glue: aggregate spidroin 1 (AgSp1)
X Li, J Mi, R Wen, J Zhang, Y Cai… - ACS Applied Bio …, 2020 - ACS Publications
Spidroin has the potential of wide applications in the biomedicine field as a natural
biomaterial. Various synthetic fibers with outstanding mechanical properties have been …
biomaterial. Various synthetic fibers with outstanding mechanical properties have been …
Conformational stability and interplay of helical N-and C-terminal domains with implications on major ampullate spidroin assembly
J Bauer, T Scheibel - Biomacromolecules, 2017 - ACS Publications
Major ampullate spidroin (MaSp) assembly starts in the abdomen of the spider, where
spidroins are stored as a liquid dope at a high concentration. The dope is squeezed into the …
spidroins are stored as a liquid dope at a high concentration. The dope is squeezed into the …
Engineered a novel pH-sensitive short major ampullate spidroin
C Zhang, J Mi, H Qi, J Huang, S Liu, L Zhang… - International journal of …, 2020 - Elsevier
The pH diversification has been proved as an important factor affecting the self-assembly of
spidroin. Herein, we constructed a novel spider silk protein (NT-MaSp1s-CT) with the pH …
spidroin. Herein, we constructed a novel spider silk protein (NT-MaSp1s-CT) with the pH …
A self-assembling peptide RADA16-I integrated with spider fibroin uncrystalline motifs
Mechanical strength of nanofiber scaffolds formed by the self-assembling peptide RADA16-I
or its derivatives is not very good and limits their application. To address this problem, we …
or its derivatives is not very good and limits their application. To address this problem, we …
Effect of functionalization on the self-assembling propensity of β-sheet forming peptides
The mechanism underlying self-assembly of short peptides has not been fully understood
despite the fact that a few decades have passed since their serendipitous discovery …
despite the fact that a few decades have passed since their serendipitous discovery …
Novel highly soluble chimeric recombinant spidroins with high yield
Q Jia, R Wen, Q Meng - International Journal of Molecular Sciences, 2020 - mdpi.com
Spider silk has been a hotspot in the study of biomaterials for more than two decades due to
its outstanding mechanical properties. Given that spiders cannot be farmed, and their low …
its outstanding mechanical properties. Given that spiders cannot be farmed, and their low …
High intracellular stability of the spidroin N‐terminal domain in spite of abundant amyloidogenic segments revealed by in‐cell hydrogen/deuterium exchange mass …
Proteins require an optimal balance of conformational flexibility and stability in their native
environment to ensure their biological functions. A striking example is spidroins, spider silk …
environment to ensure their biological functions. A striking example is spidroins, spider silk …
Properties of two spliceoforms of major ampullate spidroin 1 reveal unique functions of N-linker region
K Wang, R Wen, Q Meng - International journal of biological …, 2020 - Elsevier
Spiders produce diverse silk fibers with distinct properties for daily survival. Among these
silk fibers, dragline silk spun by major ampullate gland is used for bridgelines and web radii …
silk fibers, dragline silk spun by major ampullate gland is used for bridgelines and web radii …