Drugs of abuse-induced hyperthermia, blood-brain barrier dysfunction and neurotoxicity: neuroprotective effects of a new antioxidant compound H-290/51
HS Sharma, PO Sjoquist, SF Ali - Current pharmaceutical …, 2007 - ingentaconnect.com
The psychostimulants, morphine and methamphetamine are well known drugs of abuse that
induce brain pathology and/or neurodegeneration resulting in a huge burden on our society …
induce brain pathology and/or neurodegeneration resulting in a huge burden on our society …
Exacerbation of methamphetamine neurotoxicity in cold and hot environments: neuroprotective effects of an antioxidant compound H-290/51
In this study, we examined the influence of cold and hot environments on methamphetamine
(METH) neurotoxicity in both drug-naive rats and animals previously exposed to different …
(METH) neurotoxicity in both drug-naive rats and animals previously exposed to different …
Brain edema and breakdown of the blood–brain barrier during methamphetamine intoxication: critical role of brain hyperthermia
EA Kiyatkin, PL Brown… - European Journal of …, 2007 - Wiley Online Library
To clarify the role of brain temperature in permeability of the blood–brain barrier (BBB), rats
were injected with methamphetamine (METH 9 mg/kg) at normal (23° C) and warm (29° C) …
were injected with methamphetamine (METH 9 mg/kg) at normal (23° C) and warm (29° C) …
Amphetamine-and methamphetamine-induced hyperthermia: Implications of the effects produced in brain vasculature and peripheral organs to forebrain neurotoxicity
JF Bowyer, JP Hanig - Temperature, 2014 - Taylor & Francis
The adverse effects of amphetamine-(AMPH) and methamphetamine-(METH) induced
hyperthermia on vasculature, peripheral organs and peripheral immune system are …
hyperthermia on vasculature, peripheral organs and peripheral immune system are …
Acute methamphetamine intoxication: brain hyperthermia, blood–brain barrier, brain edema, and morphological cell abnormalities
EA Kiyatkin, HS Sharma - International review of neurobiology, 2009 - Elsevier
Methamphetamine (METH) is a powerful and often abused stimulant with potent addictive
and neurotoxic properties. While it is generally assumed that multiple chemical substances …
and neurotoxic properties. While it is generally assumed that multiple chemical substances …
Acute Administration of 3, 4‐Methylenedioxymethamphetamine Induces Profound Hyperthermia, Blood–Brain Barrier Disruption, Brain Edema Formation, and Cell …
HS Sharma, SF Ali - Annals of the New York Academy of …, 2008 - Wiley Online Library
The psychostimulant 3, 4‐, ethylenedioxymethamphetamine (MDMA,“ecstasy”) is known to
induce hyperthermia and alterations in neurochemical metabolism in the CNS. However, the …
induce hyperthermia and alterations in neurochemical metabolism in the CNS. However, the …
Leakage of the blood-brain barrier followed by vasogenic edema as the ultimate cause of death induced by acute methamphetamine overdose
EA Kiyatkin, HS Sharma - International review of neurobiology, 2019 - Elsevier
Methamphetamine (METH) is a potent CNS stimulant that is widely used as a recreational
drug. Due to its ability to increase bodily heat production and diminish heat loss due to …
drug. Due to its ability to increase bodily heat production and diminish heat loss due to …
The hidden side of drug action: brain temperature changes induced by neuroactive drugs
EA Kiyatkin - Psychopharmacology, 2013 - Springer
Rationale Most neuroactive drugs affect brain metabolism as well as systemic and cerebral
blood flow, thus altering brain temperature. Although this aspect of drug action usually …
blood flow, thus altering brain temperature. Although this aspect of drug action usually …
Cocaine-induced breakdown of the blood–brain barrier and neurotoxicity
HS Sharma, D Muresanu, A Sharma… - International review of …, 2009 - Elsevier
Role of cocaine in influencing blood–brain barrier (BBB) function is still unknown. Available
evidences suggest that cocaine administration results in acute hyperthermia and alterations …
evidences suggest that cocaine administration results in acute hyperthermia and alterations …
Breakdown of blood-brain and blood-spinal cord barriers during acute methamphetamine intoxication: role of brain temperature
EA Kiyatkin, HS Sharma - CNS & Neurological Disorders …, 2016 - ingentaconnect.com
Methamphetamine (METH) is a powerful and often-abused stimulant with potent addictive
and neurotoxic properties. While it is generally believed that structural brain damage …
and neurotoxic properties. While it is generally believed that structural brain damage …
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