Oxidative stress is an important contributor to the development of osteoporosis. Melatonin,
an indoleamine secreted by the pineal gland, has antioxidant properties. This study aims to …

Bone mass loss around prostheses is a major cause of implant failure, especially in
postmenopausal osteoporosis patients. In osteoporosis, excess oxidative stress largely …

Exogenous melatonin inhibited the senescence of preosteoblast cells in type 1 diabetic
(T1D) mice and those cultured in high glucose (HG) by multiple regulations. Exogenous …

Background The protective effect of melatonin against bone metabolism imbalance in
osteoporosis (OP) induced by drugs such as retinoic acid (RA) is unclear. The aim of this …

It was found recently that iron overload can cause osteoporosis in rats. Through in vitro and
in vivo experimentations, the purpose of the present study was to validate and confirm the …

Postmenopausal osteoporosis (OP) is one of the most common bone diseases that affects
millions of aging women. Reduced osteogenesis and increased oxidative stress have been …

Oxidative stress plays an important role in the pathogenesis of aging-related osteoporosis
through the increased bone resorption or reduced bone formation. Melatonin, which can …

Background Osteoporosis is a disease threatening the health of millions of individuals.
Melatonin is found to be a potential anti-osteoporosis drug. However, whether melatonin …

Melatonin has potent antioxidant, analgesic, and antinociceptive properties. However, the
effects of melatonin against oxidative stress‐induced cytotoxicity and inflammatory …

Osteoblastic differentiation and bone‐forming capacity are known to be suppressed under
hypoxic conditions. Melatonin has been shown to influence cell differentiation. A number of …