Healthcare utilization is a collider: an introduction to collider bias in EHR data reuse

NG Weiskopf, DA Dorr, C Jackson… - Journal of the …, 2023 - academic.oup.com
Objectives Collider bias is a common threat to internal validity in clinical research but is
rarely mentioned in informatics education or literature. Conditioning on a collider, which is a …

How and when informative visit processes can bias inference when using electronic health records data for clinical research

BA Goldstein, M Phelan, NJ Pagidipati… - Journal of the …, 2019 - academic.oup.com
Objective Electronic health records (EHR) data have become a central data source for
clinical research. One concern for using EHR data is that the process through which …

[HTML][HTML] Illustrating informed presence bias in electronic health records data: how patient interactions with a health system can impact inference

M Phelan, NA Bhavsar, BA Goldstein - EGEMs, 2017 - ncbi.nlm.nih.gov
Electronic health record (EHR) data are becoming a primary resource for clinical research.
Compared to traditional research data, such as those from clinical trials and epidemiologic …

[HTML][HTML] An empirical study for impacts of measurement errors on EHR based association studies

R Duan, M Cao, Y Wu, J Huang, JC Denny… - AMIA Annual …, 2016 - ncbi.nlm.nih.gov
Over the last decade, Electronic Health Records (EHR) systems have been increasingly
implemented at US hospitals. Despite their great potential, the complex and uneven nature …

Informative presence bias in analyses of electronic health records-derived data: a cautionary note

J Harton, N Mitra, RA Hubbard - Journal of the American Medical …, 2022 - academic.oup.com
Objective Electronic health record (EHR)-derived data are extensively used in health
research. However, the pattern of patient interaction with the healthcare system can result in …

External validation of an algorithm to identify patients with high data-completeness in electronic health records for comparative effectiveness research

KJ Lin, GE Rosenthal, SN Murphy, KD Mandl… - Clinical …, 2020 - Taylor & Francis
Objective Electronic health records (EHR) data-discontinuity, ie receiving care outside of a
particular EHR system, may cause misclassification of study variables. We aimed to validate …

On the nature of informative presence bias in analyses of electronic health records

G McGee, S Haneuse, BA Coull, MG Weisskopf… - …, 2022 - journals.lww.com
Electronic health records (EHRs) offer unprecedented opportunities to answer
epidemiologic questions. However, unlike in ordinary cohort studies or randomized trials …

A narrative review on the validity of electronic health record-based research in epidemiology

MA Gianfrancesco, ND Goldstein - BMC medical research methodology, 2021 - Springer
Electronic health records (EHRs) are widely used in epidemiological research, but the
validity of the results is dependent upon the assumptions made about the healthcare system …

Controlling for informed presence bias due to the number of health encounters in an electronic health record

BA Goldstein, NA Bhavsar, M Phelan… - American journal of …, 2016 - academic.oup.com
Electronic health records (EHRs) are an increasingly utilized resource for clinical research.
While their size allows for many analytical opportunities, as with most observational data …

[PDF][PDF] Data quality in electronic health record research: an approach for validation and quantitative bias analysis for imperfectly ascertained health outcomes via …

ND Goldstein, D Kahal, K Testa, EJ Gracely, I Burstyn - 2022 - assets.pubpub.org
It is incumbent upon all researchers who use the electronic health record (EHR), including
data scientists, to understand the quality of such data. EHR data may be subject to …