The apoptotic effects of Brucea javanica fruit extract against HT29 cells associated with p53 upregulation and inhibition of NF-κB translocation

E Bagheri, F Hajiaghaalipour… - Drug design …, 2018 - Taylor & Francis
Background Brucea javanica (L.) Merr. is a plant from the genus Brucea, which is used in
local traditional medicine to treat various diseases. Recent studies revealed an impressive …

Ethanolic extract of Brucea javanica inhibit proliferation of HCT-116 colon cancer cells via caspase activation

E Bagheri, F Hajiaghaalipour, S Nyamathulla… - RSC …, 2018 - pubs.rsc.org
Brucea javanica (L.) Merr. is a well-known plant in Chinese System of Medicine. Its fruits and
seeds have been reported to possess curative properties against various ailments. The …

Brucea javanica: A review on anticancer of its pharmacological properties and clinical researches

K Li, Y Liang, Q Wang, Y Li, S Zhou, H Wei, C Zhou… - Phytomedicine, 2021 - Elsevier
Background The dried fruits of Brucea javanica (L.) Merr (BJ) is being widely investigated,
both in lab and in clinic, to explore its potential anticancer activity and molecular mechanism …

Antiproliferative and apoptosis-inducing activity of Brucea javanica extract on human carcinoma cells

FY Lau, CH Chui, R Gambari… - International …, 2005 - spandidos-publications.com
We have recently demonstrated the antiproliferative and apoptotic activities of herbal
traditional Chinese medicines, including the analomous fruit extract of Gleditsia sinensis, the …

[HTML][HTML] Tumor cell selective cytotoxicity and apoptosis induction by an herbal preparation from Brucea javanica

H Gao, J Lamusta, WF Zhang… - … American journal of …, 2011 - ncbi.nlm.nih.gov
The plant Brucea javanica has shown impressive efficacy for treating various diseases
including cancer. However, the mechanism by which B. javanica acts is poorly understood …

Brucea javanica fruit induces cytotoxicity and apoptosis in pancreatic adenocarcinoma cell lines

ST Lau, ZX Lin, M Zhao… - Phytotherapy Research: An …, 2008 - Wiley Online Library
Brucea javanica fruit is thought to have anticancer properties in Chinese medicine and its
extract has been shown to possess antiproliferative and pro‐apoptotic activities on human …

Brucein D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase

ST Lau, ZX Lin, Y Liao, M Zhao, CHK Cheng, PS Leung - Cancer letters, 2009 - Elsevier
Pancreatic cancer is a malignant disease with extremely high mortality. Our previous work
found that Brucea javanica fruit possesses potent anti-pancreatic cancer activity. In the …

Seed Oil of Brucea javanicaInduces Cell Cycle Arrest and Apoptosis via Reactive Oxygen Species-Mediated Mitochondrial Dysfunction in Human Lung Cancer Cells

D Wang, X Qu, X Zhuang, G Geng, J Hou, N Xu… - Nutrition and …, 2016 - Taylor & Francis
Brucea javanica oil (BJO), a traditional herbal medicine extracted from the seeds of B.
javanica, has been clinically used to treat non-small cell lung cancer (NSCLC) and small cell …

(+)-Bornyl p-Coumarate Extracted from Stem of Piper betle Induced Apoptosis and Autophagy in Melanoma Cells

YJ Wu, TR Su, CI Chang, CR Chen, KF Hung… - International Journal of …, 2020 - mdpi.com
(+)-Bornyl p-coumarate is an active substance that is abundant in the Piper betle stem and
has been shown to possess bioactivity against bacteria and a strong antioxidative effect. In …

Extracts of Bridelia ovata and Croton oblongifolius induce apoptosis in human MDA‑MB‑231 breast cancer cells via oxidative stress and mitochondrial pathways

J Poofery, B Sripanidkulchai… - International …, 2020 - spandidos-publications.com
Breast cancer is the most common type of cancer and is also the second leading cause of
cancer‑associated death in women worldwide. Thus, there is an urgent requirement for the …