Cancer disease results from mutations leading to apoptosis failure and immune system
dysfunction. Because one in two people in developed counties will be diagnosed with …

Cancer is uncontrolled cell proliferation. Apoptosis controls the cells from inside while
immune system controls the cells from outside. Cancer breaks both controls. To treat cancer …

The inefficiency of the immune system to kill cancer cells leads to the disease. Like in
pregnancy, oncofetal proteins counteract the immune attack. Alpha-fetoprotein is an …

Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated
endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha …

This book examines the crucial role of a unique alpha-fetoprotein (AFP) in the treatment of
cancer. AFP can deliver toxins through specific receptors re-expressed in the majority of …

Immunotherapy is the most promising trend in cancer treatments. Checkpoint inhibitors block
the blocking molecules, enabling T-cells to target the cancer. MDSC-targeted …

The inception of targeted agents has revolutionized the cancer therapy paradigm, both for
physicians and patients. A large number of molecular targeted agents for cancer therapy are …

Today, the oncologist is like a detective of the human body who, instead of a magnifying
glass, uses the new tools of molecular pathology to search not only for genes or molecular …

Discussion Apoptosis erases the cells with unrepairable mutations. Irradiation and some
chemotherapies are used to generate those mutations in cancer cells. They expect the …

Cancer will remain a global major health problem unless new diagnostic, prognostic, and
management approaches are discovered to address both loss of life and quality of life. Here …